A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway

Y Lin, XJ Chen, JJ Li, L He, YR Yang, F Zhong… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacology relevance Sophora flavescens Aiton, was a crucial source of
Traditional Chinese Medicine (TCM) that has benefited human health for hundreds of years …

Protective Effects of Sophorae tonkinensis Gagnep. (Fabaceae) Radix et Rhizoma Water Extract on Carbon Tetrachloride-Induced Acute Liver Injury

C Zhou, A Liu, G Liu, C Yang, Q Zhou, H Li, H Yang… - Molecules, 2022 - mdpi.com
Sophorae tonkinensis Radix et Rhizoma (STR) is a traditional Chinese herbal medicine.
STR can reduce aminotransferase activity; however, the specific mechanism remains …

[HTML][HTML] Shikonin protects against D-Galactosamine and lipopolysaccharide-induced acute hepatic injury by inhibiting TLR4 signaling pathway

MX Lin, YX Yi, PP Fang, SS Huang, CW Pan, LX Jin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Shikonin, a naphthoquinone isolated from the root of medical herb Lithospermum
erythrorhizon, has been reported to have anti-inflammatory effect. However, there is no …

Inhibitory effects of nodakenin on inflammation and cell death in lipopolysaccharide-induced liver injury mice

JY Lim, JH Lee, DH Yun, YM Lee, DK Kim - Phytomedicine, 2021 - Elsevier
Background Nodakenin, a coumarin glucoside isolated from the roots of Angelica biserrata,
has been reported to have anti-inflammatory, antibacterial, anticancer effects. However …

The anti-inflammatory effects of isoflavonoids from Radix Astragali in hepatoprotective potential against LPS/D-gal-induced acute liver injury

N Aobulikasimu, D Zheng, P Guan, L Xu, B Liu… - Planta …, 2023 - thieme-connect.com
Radix Astragali (RA) is an important Traditional Chinese Medicine widely used in the
treatment of various diseases, such as pneumonia, atherosclerosis, diabetes, kidney and …

Preventive effect of flavonoids from Wushan Shencha (Malus doumeri leaves) on CCl4‐induced liver injury

K Zhu, G Huang, J Xie, X Zhou, J Mu… - Food Science & …, 2019 - Wiley Online Library
Abstract Wushan Shencha (Malus doumeri leaf) is a unique tea‐like drink. Herein, the effect
of flavonoids from Wushan Shencha (FWSSC) on carbon tetrachloride‐induced liver injury …

Research on the effectiveness and material basis of Ligusticum chuanxiong in alleviating acute liver injury

L Lu, T Lu, Y Wu, Y Wang, X Ke, R Yang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance As an effective medicinal plant, Ligusticum chuanxiong (L.
chuanxiong) is traditionally used in China to treat various kinds of dysesthesia caused by …

Protective mechanisms of wogonoside against Lipopolysaccharide/D-galactosamine-induced acute liver injury in mice

Y Gao, L Zhao, J Ma, W Xue, H Zhao - European Journal of Pharmacology, 2016 - Elsevier
Wogonoside, a bioactive flavonoid extracted from the root of Scutellaria baicalensis Georgi,
has been reported to have anti-inflammatory and antioxidant effects. In this study, we …

Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis …

H Yu, L Zheng, L Yin, L Xu, Y Qi, X Han, Y Xu… - International …, 2014 - Elsevier
The present study was to investigate the effects and possible mechanisms of the total
saponins from Dioscorea nipponica Makino (TSDN) against CCl 4-induced hepato-toxicity in …

The protective effect of Veronica ciliata Fisch. Extracts on relieving oxidative stress-induced liver injury via activating AMPK/p62/Nrf2 pathway

Q Lu, Y Shu, L Wang, G Li, S Zhang, W Gu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Veronica ciliata Fisch. existed in various Tibetan
medicine prescriptions, which was recorded to treat liver diseases in the Tibetan medicine …