Immune System Dysregulation in the Progression of Multiple Sclerosis: Molecular Insights and Therapeutic Implications
Multiple sclerosis (MS), a prevalent neurological disorder, predominantly affects young
adults and is characterized by chronic autoimmune activity. The study explores the immune …
adults and is characterized by chronic autoimmune activity. The study explores the immune …
Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting
M Charabati, MA Wheeler, HL Weiner, FJ Quintana - Cell, 2023 - cell.com
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
[HTML][HTML] Recent advances in understanding multiple sclerosis
Emerging data point to important contributions of both autoimmune inflammation and
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
Modulating inflammation and neuroprotection in multiple sclerosis
Multiple sclerosis (MS) is a neurological disorder of the central nervous system with a
presentation and disease course that is largely unpredictable. MS can cause loss of …
presentation and disease course that is largely unpredictable. MS can cause loss of …
The immunology of multiple sclerosis
KE Attfield, LT Jensen, M Kaufmann… - Nature Reviews …, 2022 - nature.com
Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis
G Mallucci, L Peruzzotti-Jametti, JD Bernstock… - Progress in …, 2015 - Elsevier
Multiple sclerosis is one of the most common causes of chronic neurological disability
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …
Toward the development of rational therapies in multiple sclerosis: what is on the horizon?
B Hemmer, HP Hartung - Annals of neurology, 2007 - Wiley Online Library
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support
an autoimmune pathogenesis on the background of a complex interaction between multiple …
an autoimmune pathogenesis on the background of a complex interaction between multiple …
Remyelination pharmacotherapy investigations highlight diverse mechanisms underlying multiple sclerosis progression
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by a complex lesion microenvironment. Although much progress has been …
characterized by a complex lesion microenvironment. Although much progress has been …
The immunopathophysiology of multiple sclerosis
GF Wu, E Alvarez - Neurologic clinics, 2011 - neurologic.theclinics.com
The cause of multiple sclerosis (MS) is elusive. However, clues to the pathogenesis of this
condition have traditionally been derived from the basic pathologic characterization of the …
condition have traditionally been derived from the basic pathologic characterization of the …
The immune response in multiple sclerosis
S Rodríguez Murúa, MF Farez… - Annual Review of …, 2022 - annualreviews.org
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …
disease that affects the central nervous system (CNS). MS is characterized by immune …