The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Skin aging is a complex process influenced by intrinsic and extrinsic factors. Together, these
factors affect the structure and function of the epidermis and dermis. Histologically, aging …

The aging process in the skin is complex and influenced by more intrinsic and extrinsic
factors than any other body organ. The effects of these two types of factors overlap for the …

Skin aging is a multifaceted process that involves intrinsic and extrinsic mechanisms that
lead to various structural and physiological changes in the skin. Intrinsic aging is associated …

Human skin is the most widespread and abundant type of tissue in the human body. With the
passage of time, most of our organs, including a substantial part of the skin, tend to undergo …

Skin aging is a multi-factorial process that affects nearly every aspect of skin biology and
function. With age, an impairment of structures, quality characteristics, and functions of the …

As the most voluminous organ of the body that is exposed to the outer environment, the skin
suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features …

The process of skin aging in humans is complex and is induced by multiple factors, including
genetic and various environmental ones. In particular, the superposition of environmental …

In recent years, skin aging has received increasing attention. Many factors affect skin aging,
and research has shown that metabolism plays a vital role in skin aging, but there needs to …

Skin is the largest organ of the human body, having the purpose of regulating temperature,
protecting us from microbes or mechanical shocks, and allowing the sensations from touch …