Autophagy: an overview and its roles in cancer and obesity
Autophagy is a normal physiological process necessary for cellular homeostasis to maintain
adequate levels of cellular components. It is essential to stabilize the source of energy …
adequate levels of cellular components. It is essential to stabilize the source of energy …
Role of autophagy in cancer prevention, development and therapy
Autophagy is a process that takes place in all mammalian cells and ensures homoeostasis
and quality control. The term autophagy [self (auto)-eating (phagy)] was first introduced in …
and quality control. The term autophagy [self (auto)-eating (phagy)] was first introduced in …
[HTML][HTML] Dual roles of autophagy and their potential drugs for improving cancer therapeutics
DW Shin - Biomolecules & Therapeutics, 2020 - ncbi.nlm.nih.gov
Autophagy is a major catabolic process that maintains cell metabolism by degrading
damaged organelles and other dysfunctional proteins via the lysosome. Abnormal …
damaged organelles and other dysfunctional proteins via the lysosome. Abnormal …
Autophagy: The spotlight for cellular stress responses
Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …
physiological processes including removing of long lived, aggregated and misfolded …
Chaperone-mediated autophagy is required for tumor growth
M Kon, R Kiffin, H Koga, J Chapochnick… - Science translational …, 2011 - science.org
The cellular process of autophagy (literally “self-eating”) is important for maintaining the
homeostasis and bioenergetics of mammalian cells. Two of the best-studied mechanisms of …
homeostasis and bioenergetics of mammalian cells. Two of the best-studied mechanisms of …
[HTML][HTML] Autophagy dysfunctions associated with cancer cells and their therapeutic implications
A Udristioiu, D Nica-Badea - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Genomic analysis of human cancers indicates that the loss or mutation of core autophagy
related genes,(ATG) is uncommon, whereas oncogenic events that activate autophagy and …
related genes,(ATG) is uncommon, whereas oncogenic events that activate autophagy and …
Autophagy and cancer
HE Karakaş, D GÖZÜAÇIK - Turkish Journal of Biology, 2014 - journals.tubitak.gov.tr
Autophagy is an evolutionary conserved intracellular degradation and stress response
mechanism that is mainly responsible for the breakdown and recycling of cytoplasmic …
mechanism that is mainly responsible for the breakdown and recycling of cytoplasmic …
Autophagy paradox of cancer: Role, regulation, and duality
AK Verma, PS Bharti, S Rafat, D Bhatt… - Oxidative Medicine …, 2021 - Wiley Online Library
Autophagy, a catabolic process, degrades damaged and defective cellular materials through
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …
Molecular mechanisms of autophagy in cancer development, progression, and therapy
VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …
important role in maintaining cellular homeostasis. It involves regulation of various genes …
[HTML][HTML] Unfolding the role of autophagy in the cancer metabolism
Autophagy is considered an indispensable process that scavenges toxins, recycles complex
macromolecules, and sustains the essential cellular functions. In addition to its …
macromolecules, and sustains the essential cellular functions. In addition to its …