Progress in the treatment of drug-induced liver injury with natural products
Y Sun, Y Zhang, L Xie, F Rong, X Zhu, J Xie… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …
Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs
Y Zhou, J Wang, D Zhang, J Liu, Q Wu, J Chen, P Tan… - Chinese medicine, 2021 - Springer
Drug-induced liver injury (DILI) is a common adverse drug reaction (ADR) and a serious
threat to health that affects disease treatments. At present, no targeted clinical drugs are …
threat to health that affects disease treatments. At present, no targeted clinical drugs are …
Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects
Drug‐induced liver injury (DILI) refers to adverse reactions to small chemical compounds,
biological agents, and medical products. These reactions can manifest as acute or chronic …
biological agents, and medical products. These reactions can manifest as acute or chronic …
Novel therapies for the treatment of drug-induced liver injury: a systematic review
MS Benić, L Nežić, V Vujić-Aleksić… - Frontiers in …, 2022 - frontiersin.org
Many drugs with different mechanisms of action and indications available on the market
today are capable of inducing hepatotoxicity. Drug-induced liver injury (DILI) has been a …
today are capable of inducing hepatotoxicity. Drug-induced liver injury (DILI) has been a …
Glycyrrhizin mediated liver-targeted alginate nanogels delivers quercetin to relieve acute liver failure
FQ Zhao, GF Wang, D Xu, HY Zhang, YL Cui… - International Journal of …, 2021 - Elsevier
Acute liver failure is an uncommon and dramatic clinical syndrome with a high risk of
mortality. Previous treatments existed some limitations of poor bioavailability and targeting …
mortality. Previous treatments existed some limitations of poor bioavailability and targeting …
Evaluation of the hepatoprotective effect of naringenin loaded nanoparticles against acetaminophen overdose toxicity
R Lu, RJ Yu, C Yang, Q Wang, Y Xuan, Z Wang… - Drug Delivery, 2022 - Taylor & Francis
Acute liver injury is a common clinical disease, which easily leads to liver failure and
endangers life, seriously threatening human health. Naringenin is a natural flavonoid that …
endangers life, seriously threatening human health. Naringenin is a natural flavonoid that …
Ginsenoside Rg3 ameliorates acetaminophen-induced hepatotoxicity by suppressing inflammation and oxidative stress
Y Gao, J Yan, J Li, X Li, S Yang, N Chen… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Improper usage of acetaminophen (APAP) leads to morbidity and also mortality
secondary to liver damage. Ginseng could suppress APAP-induced hepatotoxicity and …
secondary to liver damage. Ginseng could suppress APAP-induced hepatotoxicity and …
Molecular mechanism and research progress on pharmacology of traditional Chinese medicine in liver injury
HY Zhang, HL Wang, GY Zhong, JX Zhu - Pharmaceutical biology, 2018 - Taylor & Francis
Context: Liver disease is a common threat to human health, caused by a variety of factors
that damage the liver. Recent studies have shown that active ingredients (for example …
that damage the liver. Recent studies have shown that active ingredients (for example …
[HTML][HTML] Drug-induced liver injury and prospect of cytokine based therapy; A focus on IL-2 based therapies
Drug-induced liver injury (DILI) is one of the most frequent sources of liver failure and the
leading cause of liver transplant. Common non-prescription medications such as non …
leading cause of liver transplant. Common non-prescription medications such as non …
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro
C Ning, X Gao, C Wang, Y Kong, Z Liu, H Sun… - Regulatory Toxicology …, 2018 - Elsevier
Acetaminophen (APAP) is a worldwide used drug for treating fever and pain. However,
APAP overdose is the leading cause of drug-induced liver injury. The purpose of the current …
APAP overdose is the leading cause of drug-induced liver injury. The purpose of the current …
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