Alzheimer disease (AD) is a progressive neurodegenerative disorder characterized by
excessive deposition of amyloid-β (Aβ) peptides in the brain. One of the earliest …

Astrocytes and microglia are able to degrade potentially neurotoxic β‐amyloid (Aβ) deposits
typical for Alzheimer's disease (AD) pathology. Contrary to microglia, astrocytes degrade …

Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive
abilities, and even their personalities may change dramatically. These changes are due to …

Alzheimer's disease (AD) is one of the most devastating neurodegenerative disorders. The
neuropathological hallmarks include extracellular senile plaques consisting of deposited β …

The incidence of Alzheimer's disease (AD), the leading cause of dementia, increases rapidly
with age, but why age constitutes the main risk factor is still poorly understood. Brain ageing …

Communication within the glial cell ecosystem is essential for neuronal and brain health,–.
The influence of glial cells on the accumulation and clearance of β-amyloid (Aβ) and …

The formation of fibrillar deposits of amyloid β protein (Aβ) in the brain is a pathological
hallmark of Alzheimer's disease1, 2 (AD). A central question is whether Aβ plays a direct role …

The role of astrocytes in the progression of Alzheimer's disease (AD) remains poorly
understood. We assessed the consequences of ablating astrocytic proliferation in 9 months …

Abnormal accumulation of the amyloid-β peptide (Aβ) in the brain appears crucial to
pathogenesis in all forms of Alzheimer disease (AD), but the underlying mechanisms in the …

Alzheimer's disease is a progressive loss of memory and cognition, for which there is no
cure. Although genetic studies initially suggested a primary role for amyloid-in Alzheimer's …