Traditional Chinese medicine, such as Tripterygium wilfordii and Paeonia lactiflora, has
potential values in treating systemic sclerosis (SSc) and other autoimmune diseases, while …

Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

Emerging biologics, such as monoclonal antibodies (mAbs), are the most promising
treatment for psoriasis, while their effective delivery to the local inflammatory area of the skin …

Microneedle patches (MNs) have demonstrated potentials in transdermal drug delivery for
skin disease therapy. Effort is mainly focused on the improvement of MNs' materials …

Hypertrophic scar (HS) considerably affects the appearance and causes tissue dysfunction
in patients. The low bioavailability of 5-fluorouracil poses a challenge for HS treatment. Here …

Microneedle (MN) patches are promising stratagems for transdermal drug delivery owing to
its minimal invasiveness and portability. Particularly, separable MN patches attract more …

Abstract Background Systemic sclerosis (SSc) is a disease that features severe fibrosis of
the skin and lacks effective therapy. Bone marrow mesenchymal stem cell (BMSC)-derived …

Purpose Oxidative stress, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-
κB) and adenosine signaling are factors associated with psoriatic inflammation. Topical …

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Antioxidative treatment
combined with chemotherapy holds great promise for RA treatment, and the ability to …

Hypertrophic scars are unfavorable skin diseases characterized by excessive collagen
deposition. Although systemic treatments exist in clinic to manage hypertrophic scars, they …