Different variants of hepatitis C virus core protein (HCcAg) have proved to self-assemble in
vitro into virus-like particles (VLPs). However, difficulties in obtaining purified mature HCcAg …

Little is known about the assembly pathway or structure of the hepatitis C virus (HCV). In this
work a truncated HCcAg variant covering the first 120 aa (HCcAg. 120) with a 32 aa N …

The in vitro self-assembly properties of the entire hepatitis C virus core protein (HCcAg)
obtained from Pichia pastoris cells and the induction of specific antibody immune response …

Little is known about the in vivo assembly pathway or structure of the hepatitis C virus
nucleocapsid. In this work the intermediates of HCcAg multimerization in Pichia pastoris …

Little is known about the mechanism of hepatitis C virion assembly. So the capacity of the
entire Hepatitis C virus core protein (HCcAg) produced in Pichia pastoris to form particles …

Little is known about the assembly pathway and structure of hepatitis C virus (HCV) since
insufficient quantities of purified virus are available for detailed biophysical and structural …

Core protein is one of the most conserved and immunogenic of the hepatitis C virus proteins.
Several pieces of experimental evidence suggest its ability for formation of virus like …

The assembly of hepatitis C virus (HCV) is poorly understood, largely due to the lack of
mammalian cell culture systems that are easily manipulated and produce high titers of virus …

The hepatitis C virus (HCV) core protein is involved in the assembly of nucleocapsid
particles, as well as regulation of cellular and viral gene expression. To investigate the …

Although a number of recent studies have suggested that the function of the hepatitis C virus
(HCV) core protein may be both to package the viral genome and to modulate host cellular …