Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family
ER Geertsma, YN Chang, FR Shaik… - Nature structural & …, 2015 - nature.com
The SLC26 family of membrane proteins combines a variety of functions within a conserved
molecular scaffold. Its members, besides coupled anion transporters and channels, include …
molecular scaffold. Its members, besides coupled anion transporters and channels, include …
Structure of the cytosolic portion of the motor protein prestin and functional role of the STAS domain in SLC26/SulP anion transporters
E Pasqualetto, R Aiello, L Gesiot, G Bonetto… - Journal of molecular …, 2010 - Elsevier
Prestin is the motor protein responsible for the somatic electromotility of cochlear outer hair
cells and is essential for normal hearing sensitivity and frequency selectivity of mammals …
cells and is essential for normal hearing sensitivity and frequency selectivity of mammals …
[HTML][HTML] Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters
D Gorbunov, M Sturlese, F Nies, M Kluge… - Nature …, 2014 - nature.com
Abstract Prestin (SLC26A5) is a member of the SLC26/SulP anion transporter family. Its
unique quasi-piezoelectric mechanical activity generates fast cellular motility of cochlear …
unique quasi-piezoelectric mechanical activity generates fast cellular motility of cochlear …
[HTML][HTML] Conserved dimeric subunit stoichiometry of SLC26 multifunctional anion exchangers
S Detro-Dassen, M Schanzler, H Lauks, I Martin… - Journal of Biological …, 2008 - ASBMB
The SLC26 gene family encodes multifunctional transport proteins in numerous tissues and
organs. Some paralogs function as anion exchangers, others as anion channels, and one …
organs. Some paralogs function as anion exchangers, others as anion channels, and one …
[HTML][HTML] Single particle cryo-EM structure of the outer hair cell motor protein prestin
C Butan, Q Song, JP Bai, WJT Tan… - Nature …, 2022 - nature.com
The mammalian outer hair cell (OHC) protein prestin (Slc26a5) differs from other Slc26
family members due to its unique piezoelectric-like property that drives OHC electromotility …
family members due to its unique piezoelectric-like property that drives OHC electromotility …
Nonmammalian orthologs of prestin (SLC26A5) are electrogenic divalent/chloride anion exchangers
TJ Schaechinger, D Oliver - Proceedings of the National …, 2007 - National Acad Sciences
Individual members of the mammalian SLC26 anion transporter family serve two
fundamentally distinct functions. Whereas most members transport different anion substrates …
fundamentally distinct functions. Whereas most members transport different anion substrates …
The conformational cycle of prestin underlies outer-hair cell electromotility
The voltage-dependent motor protein prestin (also known as SLC26A5) is responsible for
the electromotive behaviour of outer-hair cells and underlies the cochlear amplifier …
the electromotive behaviour of outer-hair cells and underlies the cochlear amplifier …
[HTML][HTML] Prestin's anion transport and voltage-sensing capabilities are independent
JP Bai, A Surguchev, S Montoya, PS Aronson… - Biophysical journal, 2009 - cell.com
The integral membrane protein prestin, a member of the SLC26 anion transporter family, is
responsible for the voltage-driven electromotility of mammalian outer hair cells. It was …
responsible for the voltage-driven electromotility of mammalian outer hair cells. It was …
From zebrafish to mammal: functional evolution of prestin, the motor protein of cochlear outer hair cells
X Tan, JL Pecka, J Tang, OE Okoruwa… - Journal of …, 2011 - journals.physiology.org
Prestin is the motor protein of cochlear outer hair cells. It belongs to a distinct anion
transporter family called solute carrier protein 26A, or SLC26A. Members of this family serve …
transporter family called solute carrier protein 26A, or SLC26A. Members of this family serve …
Substrate-dependent proton antiport in neurotransmitter: sodium symporters
Y Zhao, M Quick, L Shi, EL Mehler, H Weinstein… - Nature chemical …, 2010 - nature.com
Abstract Neurotransmitter-sodium symporters (NSS), targets for psychostimulants and
therapeutic drugs, have a critical role in neurotransmission. Whereas eukaryotic NSS show …
therapeutic drugs, have a critical role in neurotransmission. Whereas eukaryotic NSS show …