[HTML][HTML] Clinical measures of bulbar dysfunction in ALS

Y Yunusova, EK Plowman, JR Green, C Barnett… - Frontiers in …, 2019 - frontiersin.org
Bulbar impairment represents a hallmark feature of Amyotrophic Lateral Sclerosis (ALS) that
significantly impacts survival and quality of life. Speech and swallowing dysfunction are key …

Provisional best practices guidelines for the evaluation of bulbar dysfunction in amyotrophic lateral sclerosis

GL Pattee, EK Plowman, KL Garand, J Costello… - Muscle & …, 2019 - Wiley Online Library
Introduction: Universally established comprehensive clinical bulbar scales objectively
assessing disease progression in amyotrophic lateral sclerosis (ALS) are currently lacking …

Assessment of bulbar function in amyotrophic lateral sclerosis: validation of a self‐report scale (Center for Neurologic Study Bulbar Function Scale)

RA Smith, EA Macklin, KJ Myers… - European journal of …, 2018 - Wiley Online Library
Background and purpose Impaired bulbar functions of speech and swallowing are among
the most serious consequences of amyotrophic lateral sclerosis (ALS). Despite this, clinical …

Bulbar and speech motor assessment in ALS: Challenges and future directions

JR Green, Y Yunusova, MS Kuruvilla… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
Bulbar motor deterioration due to amyotrophic lateral sclerosis (ALS) leads to the eventual
impairment of speech and swallowing functions. Despite these devastating consequences …

The evaluation of bulbar dysfunction in amyotrophic lateral sclerosis: survey of clinical practice patterns in the United States

EK Plowman, LC Tabor, J Wymer… - … Lateral Sclerosis and …, 2017 - Taylor & Francis
Objective: Speech and swallowing impairments are highly prevalent in individuals with
amyotrophic lateral sclerosis (ALS) and contribute to reduced quality of life, malnutrition …

Assessment of dysarthria and dysphagia in patients with amyotrophic lateral sclerosis: Review of the current evidence

J Lee, A Madhavan, E Krajewski… - Muscle & …, 2021 - Wiley Online Library
Bulbar dysfunction is a common presentation of amyotrophic lateral sclerosis (ALS) and
significantly impacts quality of life of people with ALS (PALS). The current paper reviews …

Predicting early bulbar decline in amyotrophic lateral sclerosis: A speech subsystem approach

P Rong, Y Yunusova, J Wang… - Behavioural neurology, 2015 - Wiley Online Library
Purpose. To develop a predictive model of speech loss in persons with amyotrophic lateral
sclerosis (ALS) based on measures of respiratory, phonatory, articulatory, and resonatory …

Diagnosis and treatment of bulbar symptoms in amyotrophic lateral sclerosis

P Kühnlein, HJ Gdynia, AD Sperfeld… - Nature clinical practice …, 2008 - nature.com
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease of the
motor system. Bulbar symptoms such as dysphagia and dysarthria are frequent features of …

The diagnostic utility of patient-report and speech-language pathologists' ratings for detecting the early onset of bulbar symptoms due to ALS

KM Allison, Y Yunusova, TF Campbell… - … Lateral Sclerosis and …, 2017 - Taylor & Francis
Objective: This study aimed to determine the diagnostic utility of clinician speech ratings and
patient self-report for detecting early bulbar changes associated with amyotrophic lateral …

[HTML][HTML] Early detection and tracking of bulbar changes in ALS via frequent and remote speech analysis

GM Stegmann, S Hahn, J Liss, J Shefner… - NPJ digital …, 2020 - nature.com
Bulbar deterioration in amyotrophic lateral sclerosis (ALS) is a devastating characteristic that
impairs patients' ability to communicate, and is linked to shorter survival. The existing clinical …