[HTML][HTML] Strategies for drawing quantitative conclusions from nontargeted liquid chromatography–high-resolution mass spectrometry analysis

A Kruve - 2020 - ACS Publications
This Feature aims at giving an overview of different possibilities for quantitatively comparing
the results obtained from LC− HRMS-based nontargeted analysis. More specifically …

Validation of the mass-extraction-window for quantitative methods using liquid chromatography high resolution mass spectrometry

G Glauser, B Grund, AL Gassner, L Menin… - Analytical …, 2016 - ACS Publications
A paradigm shift is underway in the field of quantitative liquid chromatography–mass
spectrometry (LC-MS) analysis thanks to the arrival of recent high-resolution mass …

Semi-targeted residue screening in complex matrices with liquid chromatography coupled to high resolution mass spectrometry: current possibilities and limitations

A Kaufmann, P Butcher, K Maden, S Walker, M Widmer - Analyst, 2011 - pubs.rsc.org
Some twenty cultured fish samples were analyzed for possible residues of veterinary drugs
with high resolution mass spectrometry (single stage Orbitrap) coupled to ultra performance …

Quantitative and confirmative performance of liquid chromatography coupled to high‐resolution mass spectrometry compared to tandem mass spectrometry

A Kaufmann, P Butcher, K Maden… - Rapid …, 2011 - Wiley Online Library
The quantitative and confirmative performance of two different mass spectrometry (MS)
techniques (high‐resolution MS and tandem MS) was critically compared. Evaluated was a …

General strategies to increase the repeatability in non-target screening by liquid chromatography-high resolution mass spectrometry

T Bader, W Schulz, K Kümmerer, R Winzenbacher - Analytica chimica acta, 2016 - Elsevier
This article focuses on the data evaluation of non-target high-resolution LC-MS profiles of
water samples. Taking into account multiple technical replicates, the difficulties in peak …

Nontarget analysis of environmental samples based on liquid chromatography coupled to high resolution mass spectrometry (LC-HRMS)

P Gago-Ferrero, EL Schymanski, J Hollender… - Comprehensive …, 2016 - Elsevier
The chemical pollutants that are (inter) nationally regulated represent a very small fraction of
the universe of chemicals that occur in the environment as a result of human activities …

Accurate mass determination, quantification and determination of detection limits in liquid chromatography–high-resolution time-of-flight mass spectrometry …

L Vergeynst, H Van Langenhove, P Joos… - Analytica Chimica …, 2013 - Elsevier
Uniform guidelines for the data processing and validation of qualitative and quantitative
multi-residue analysis using full-spectrum high-resolution mass spectrometry are scarce …

[HTML][HTML] Guide to semi-quantitative non-targeted screening using LC/ESI/HRMS

L Malm, E Palm, A Souihi, M Plassmann, J Liigand… - Molecules, 2021 - mdpi.com
Non-targeted screening (NTS) with reversed phase liquid chromatography electrospray
ionization high resolution mass spectrometry (LC/ESI/HRMS) is increasingly employed as …

From targeted quantification to untargeted metabolomics: Why LC-high-resolution-MS will become a key instrument in clinical labs

B Rochat - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Most late model high-resolution mass spectrometers (HRMS) are capable of performing
sensitive and reliable quantifications of a large variety of analytes in global HR-full scan (HR …

Advances in liquid chromatography–high-resolution mass spectrometry for quantitative and qualitative environmental analysis

J Aceña, S Stampachiacchiere, S Pérez… - Analytical and …, 2015 - Springer
This review summarizes the advances in environmental analysis by liquid chromatography–
high-resolution mass spectrometry (LC–HRMS) during the last decade and discusses …