Background: Hepatic sarcopenia is one of many complications associated with chronic liver
disease (CLD) and has a high mortality rate; however, the liver-muscle axis is not fully …

The gut‑liver‑muscle axis is associated with the development of sarcopenia in liver cirrhosis.
The present study aimed to illustrate the combined effects of rifaximin and L‑carnitine on …

Cirrhosis-associated muscle mass loss or sarcopenia is a common complication (17-30%
prevalence) in cirrhotic patients. However, the pathogenesis of this complication is poorly …

Lithocholic acid (LCA) is a classical secondary bile acid formed by the metabolism of gut
microbiota. The TGR5 receptor (also known as G protein-coupled receptor 1, GPBAR1) is an …

Cholestatic chronic liver disease is characterized by developing sarcopenia and elevated
serum levels of bile acids. Sarcopenia is a skeletal muscle disorder with the hallmarks of …

Sarcopenia associated with chronic liver disease (CLD) is one of the more common
extrahepatic features in patients with these pathologies. Among the cellular alterations …

Objective Sarcopenia is characterized by the loss of skeletal muscle mass, and is reported to
appear in patients with liver cirrhosis (LC). The aim of this study was to investigate the …

Liver cirrhosis is frequently accompanied by disease-related malnutrition (DRM) and
sarcopenia, defined as loss of skeletal muscle mass and function. DRM and sarcopenia …

Skeletal muscle loss (sarcopenia) is a major clinical complication in alcoholic cirrhosis with
no effective therapy. Skeletal muscle autophagic proteolysis and myostatin expression …

Sarcopenia, a condition of low muscle mass, quality, and strength, is commonly found in
patients with chronic liver disease (CLD) and is associated with adverse clinical outcomes …