One-carbon metabolism and epigenetic programming of mammalian development

CE Clare - 2021 - eprints.nottingham.ac.uk
One-carbon (1C) metabolism comprises a series of integrated metabolic pathways,
including the linked methionine-folate cycles, that provide methyl groups for the synthesis of …

One-carbon metabolism: linking nutritional biochemistry to epigenetic programming of long-term development

CE Clare, AH Brassington, WY Kwong… - Annual review of …, 2019 - annualreviews.org
One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

One-carbon metabolism and epigenetic regulation of embryo development

J Xu, KD Sinclair - Reproduction, Fertility and Development, 2015 - CSIRO Publishing
One-carbon (1C) metabolism consists of an integrated series of metabolic pathways that
include the folate cycle and methionine remethylation and trans-sulfuration pathways. Most …

390 Micronutrients, One-Carbon Metabolism, and Epigenetics: Potential Developmental and Production Outcomes

MS Crouse, J Caton, AK Ward - Journal of Animal Science, 2020 - academic.oup.com
One-carbon metabolism is the network of biochemical pathways in which methyl groups are
transferred from one compound to another for methylation processes. Expansion of the core …

Interspecific variation in one-carbon metabolism within the ovarian follicle, oocyte, and preimplantation embryo: consequences for epigenetic programming of DNA …

CE Clare, V Pestinger, WY Kwong, DAR Tutt… - International Journal of …, 2021 - mdpi.com
One-carbon (1C) metabolism provides methyl groups for the synthesis and/or methylation of
purines and pyrimidines, biogenic amines, proteins, and phospholipids. Our understanding …

One-carbon metabolite supplementation improves growth of bovine embryonic fibroblasts cultured in divergent glucose media

MS Crouse, JS Caton, ACB Menezes… - Translational Animal …, 2019 - academic.oup.com
One-carbon metabolism is the network of biochemical pathways that regulates amino acid
metabolism, nucleotide synthesis, and epigenetic processes, such as methylation and …

Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions

S Ikeda, R Kawahara-Miki, H Iwata, M Sugimoto… - Scientific reports, 2017 - nature.com
Methionine adenosyltransferase (MAT) is involved in folate-mediated one-carbon
metabolism, which is essential for preimplantation embryos in terms of both short-term …

B-vitamins & one-carbon metabolism: Impacts on the epigenome during development

KE Sant, OS Anderson - Nutritional Epigenomics, 2019 - Elsevier
The embryonic and fetal periods of development are times of substantial programming and
growth, which establish a foundation for health throughout the life-course. During this time …

Roles of One-carbon Metabolism in Preimplantation Period—Effects on Short-term Development and Long-term Programming—

S Ikeda, H Koyama, M Sugimoto… - Journal of Reproduction …, 2012 - jstage.jst.go.jp
One-carbon metabolism (OCM) can be seen as integrated metabolic pathways centered on
the metabolism of two nutritional substances, folate and methionine. Mammalian oocytes …

Effects of Moderate Nutrient Restriction in Beef Cattle During Early Gestation on One-Carbon Metabolite Concentrations in Maternal and Fetal Tissues

JG Syring - 2023 - search.proquest.com
Times of nutrient restriction for beef cattle often occur during gestation, leading to short-and
long-term impacts on the developing fetus. Many of those impacts are programmed via …