Background Small airway dysfunction (SAD) is a widespread but less typical clinical
manifestation of respiratory dysfunction. In lung diseases, SAD can have a higher-than …

Background Small airway dysfunction is a common but neglected respiratory abnormality.
Little is known about its prevalence, risk factors, and prognostic factors in China or anywhere …

Background Small airway dysfunction (SAD) and airway inflammation are vital in asthma
exacerbations. Type 2 inflammation (T2), mediated by cytokines from T helper 2 cell (Th2) …

Background Small airway dysfunction (SAD) and impaired diffusion capacity of the lungs for
carbon monoxide (DL CO) are positively associated with a worse prognosis. Individuals with …

Background Small airways dysfunction (SAD) in asthma is difficult to measure and a gold
standard is lacking. The aim of this study was to develop a simple tool including items of the …

Background Aging has been evidenced to bring about some structural and functional lung
changes, especially in COPD. However, whether aging affects SAD, a possible precursor of …

Objectives This study aimed to identify the potential risk factors for small airway dysfunction
(SAD) in non-smokers with chronic cough. Methods Non-smokers with chronic cough who …

Background Small airway dysfunction not only affects asthma control, but also has adverse
effects on the psychological and/or social activities of asthma patients. However, few long …

Background: Emerging evidence has indicated that small airway dysfunction (SAD)
contributes to the clinical expression of asthma. Objectives: The aim of the study was to …

Introduction Small airway dysfunction (SAD) caused by smoking contributes to the early
onset of airflow limitation (AFL), although its impact on patients' perception of health is …