Essential gene discovery in the basidiomycete Cryptococcus neoformans for antifungal drug target prioritization
Fungal diseases represent a major burden to health care globally. As with other pathogenic
microbes, there is a limited number of agents suitable for use in treating fungal diseases …
microbes, there is a limited number of agents suitable for use in treating fungal diseases …
Genetic Manipulation of Cryptococcus neoformans
KW Jung, KT Lee, YS So… - Current Protocols in …, 2018 - Wiley Online Library
Cryptococcus neoformans is an opportunistic fungal pathogen, which causes life‐
threatening meningoencephalitis in immunocompromised individuals and is responsible for …
threatening meningoencephalitis in immunocompromised individuals and is responsible for …
Combatting the evolution of antifungal resistance in Cryptococcus neoformans
A Bermas, J Geddes‐McAlister - Molecular microbiology, 2020 - Wiley Online Library
Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
Evidence for genetic incompatibilities associated with post-zygotic reproductive isolation in the human fungal pathogen Cryptococcus neoformans
Hybridization is a potent mechanism for generating unique strains with broad host ranges
and increased virulence in fungal pathogens. In the opportunistic basidiomycete pathogen …
and increased virulence in fungal pathogens. In the opportunistic basidiomycete pathogen …
Progress in functional genomics approaches to antifungal drug target discovery
MD De Backer, P Van Dijck - Trends in microbiology, 2003 - cell.com
Antifungal drug discovery is starting to benefit from the enormous advances in the genomics
field, which have occurred in the past decade. As traditional drug screening on existing …
field, which have occurred in the past decade. As traditional drug screening on existing …
[HTML][HTML] Connecting virulence pathways to cell-cycle progression in the fungal pathogen Cryptococcus neoformans
CM Kelliher, SB Haase - Current Genetics, 2017 - Springer
Proliferation and host evasion are critical processes to understand at a basic biological level
for improving infectious disease treatment options. The human fungal pathogen …
for improving infectious disease treatment options. The human fungal pathogen …
[HTML][HTML] Importance of Clinical Isolates in Cryptococcus neoformans Research
KM Jackson, M Ding, K Nielsen - Journal of Fungi, 2023 - mdpi.com
The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …
Previous research in the field has focused on studies using reference strains to identify …
An intergenic “safe haven” region in Cryptococcus neoformans serotype D genomes
Y Fan, X Lin - Fungal Genetics and Biology, 2020 - Elsevier
Cryptococcus neoformans is an opportunistic human fungal pathogen and serves as a
model organism for studies of eukaryotic microbiology and microbial pathogenesis. C …
model organism for studies of eukaryotic microbiology and microbial pathogenesis. C …
Novel strategies in antifungal lead discovery
B Jiang, H Bussey, T Roemer - Current opinion in microbiology, 2002 - Elsevier
There have been significant developments in fungal genomics over the past year. The
recently released genome sequences of Aspergillus fumigatus and Cryptococcus …
recently released genome sequences of Aspergillus fumigatus and Cryptococcus …
A PCR-based strategy to generate integrative targeting alleles with large regions of homology
RC Davidson, JR Blankenship, PR Kraus… - …, 2002 - microbiologyresearch.org
Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle
for which genetic and molecular techniques are well developed. The entire genome …
for which genetic and molecular techniques are well developed. The entire genome …