Divergent expression of liver transforming growth factor superfamily cytokines after successful portoenterostomy in biliary atresia
A Kerola, J Lohi, P Heikkilä, A Mutanen, H Jalanko… - Surgery, 2019 - Elsevier
Background Pathogenesis of progressive liver fibrosis in biliary atresia after successful
portoenterostomy remains unclear. We related hepatic expression of transforming growth …
portoenterostomy remains unclear. We related hepatic expression of transforming growth …
Molecular signature of active fibrogenesis prevails in biliary atresia after successful portoenterostomy
A Kerola, H Lampela, J Lohi, P Heikkilä, A Mutanen… - Surgery, 2017 - Elsevier
Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …
transplantation after successful portoenterostomy remain unknown. A better understanding …
Identification of transforming growth factors actively transcribed during the progress of liver fibrosis in biliary atresia
SY Lee, JH Chuang, CC Huang, MH Chou… - Journal of pediatric …, 2004 - Elsevier
BACKGROUND/PURPOSE: Transforming growth factor-beta (TGF-β) 1 and 2 and their
receptors TβR-I, TβR-II, and TβR-III are powerful profibrogenic mediators in the body. Their …
receptors TβR-I, TβR-II, and TβR-III are powerful profibrogenic mediators in the body. Their …
Increased MMP‐7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia
A Kerola, H Lampela, J Lohi, P Heikkilä… - The Journal of …, 2016 - Wiley Online Library
The molecular mechanisms underlying progressive liver fibrosis following surgical treatment
of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein …
of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein …
Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia
GA Ramm, VG Nair, KR Bridle, RW Shepherd… - The American journal of …, 1998 - Elsevier
Extrahepatic biliary atresia is a severe neonatal liver disease resulting from a sclerosing
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …
Immunohistochemical localization of transforming growth factor β-1 and its relationship with collagen expression in advanced liver fibrosis due to biliary atresia
C Farrington, D Novak, C Liu… - Clinical and experimental …, 2010 - Taylor & Francis
Purpose: Biliary atresia (BA) is the most common indication of liver transplantation in
children. Pathogenesis of hepatic fibrosis, which is a prominent feature of BA, remains …
children. Pathogenesis of hepatic fibrosis, which is a prominent feature of BA, remains …
[PDF][PDF] Evolving Up‐regulation of Biliary Fibrosis–Related Extracellular Matrix Molecules After Successful Portoenterostomy
A Kyrönlahti, N Godbole, O Akinrinade… - Hepatology …, 2021 - Wiley Online Library
Successful portoenterostomy (SPE) improves the short‐term outcome of patients with biliary
atresia (BA) by relieving cholestasis and extending survival with native liver. Despite SPE …
atresia (BA) by relieving cholestasis and extending survival with native liver. Despite SPE …
Connective tissue growth factor and progressive fibrosis in biliary atresia
H Kobayashi, N Hayashi, K Hayashi… - Pediatric surgery …, 2005 - Springer
Connective tissue growth factor (CTGF) is a newly described protein that stimulates
transforming growth factor-β1 (TGF-β1). We evaluated the expression of CTGF mRNA in …
transforming growth factor-β1 (TGF-β1). We evaluated the expression of CTGF mRNA in …
Serum transforming growth factor-β1 and epidermal growth factor in biliary atresia
P Vejchapipat, A Theamboonlers… - European journal of …, 2008 - thieme-connect.com
Abstract Background and Aim: Biliary atresia (BA) is a serious liver disease in children.
Since transforming growth factor-β1 (TGF-β1) and epidermal growth factor (EGF) are …
Since transforming growth factor-β1 (TGF-β1) and epidermal growth factor (EGF) are …
Serum FGF19 predicts outcomes of Kasai portoenterostomy in biliary atresia
I Nyholm, M Hukkinen, M Pihlajoki, JR Davidson… - Hepatology, 2023 - journals.lww.com
Serum FGF19 predicts outcomes of Kasai portoenterostomy in b... : Hepatology Serum FGF19
predicts outcomes of Kasai portoenterostomy in biliary atresia : Hepatology AASLD Publications …
predicts outcomes of Kasai portoenterostomy in biliary atresia : Hepatology AASLD Publications …
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