The role of dendritic cells in the immunomodulation to implanted biomaterials

S Wang, Y Chen, Z Ling, J Li, J Hu, F He… - International Journal of …, 2022 - nature.com
Considering the substantial role played by dendritic cells (DCs) in the immune system to
bridge innate and adaptive immunity, studies on DC-mediated immunity toward biomaterials …

Role of dendritic cells in the host response to biomaterials and their signaling pathways

F Zhu, Y Tong, Z Sheng, Y Yao - Acta biomaterialia, 2019 - Elsevier
Strategies to enhance, inhibit, or qualitatively modulate immune responses are important for
diverse biomedical applications such as vaccine adjuvant, drug delivery, immunotherapy …

Dendritic cells in the host response to implanted materials

BG Keselowsky, JS Lewis - Seminars in immunology, 2017 - Elsevier
The role of dendritic cells (DCs) and their targeted manipulation in the body's response to
implanted materials is an important and developing area of investigation, and a large …

Dendritic cells in host response to biologic scaffolds

CA Leifer - Seminars in immunology, 2017 - Elsevier
Tissue regeneration and repair require a highly complex and orchestrated series of events
that require inflammation, but can be compromised when inflammation is excessive or …

Dendritic cells as targets for biomaterial-based immunomodulation

F Eslami-Kaliji, M Sarafbidabad… - ACS Biomaterials …, 2020 - ACS Publications
Various subtypes of immunocytes react against implanted biomaterials to eliminate the
foreign body object from the host's body. Among these cells, dendritic cells (DCs) play a key …

Macrophage and dendritic cell phenotypic diversity in the context of biomaterials

PM Kou, JE Babensee - Journal of biomedical materials …, 2011 - Wiley Online Library
Macrophages (Mϕ) and dendritic cells (DCs) are critical antigen presenting cells that play
pivotal roles in host responses to biomaterial implants. Although Mϕs have been widely …

Innate immunity and biomaterials at the nexus: friends or foes

SN Christo, KR Diener, A Bachhuka… - BioMed research …, 2015 - Wiley Online Library
Biomaterial implants are an established part of medical practice, encompassing a broad
range of devices that widely differ in function and structural composition. However, one …

Validation of a high-throughput methodology to assess the effects of biomaterials on dendritic cell phenotype

PM Kou, JE Babensee - Acta biomaterialia, 2010 - Elsevier
A variety of combination products composed of biomaterials and biologics have been
developed for tissue regeneration or vaccine delivery. The host immune response to the …

Adhesive substrate-modulation of adaptive immune responses

AP Acharya, NV Dolgova, MJ Clare-Salzler… - Biomaterials, 2008 - Elsevier
While it is well-known that adsorbed proteins on implanted biomaterials modulate
inflammatory responses, modulation of dendritic cells (DCs) via adhesion-dependent …

Material matters: exploring the interplay between natural biomaterials and host immune system

AS Tripathi, MEA Zaki, SA Al-Hussain… - Frontiers in …, 2023 - frontiersin.org
Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …