Shielding and stealth effects of zwitterion moieties in double-functionalized silica nanoparticles

LMD Loiola, M Batista, LB Capeletti, GB Mondo… - Journal of colloid and …, 2019 - Elsevier
Surface functionalization of silica nanoparticles (SiO 2 NPs) has been considered as a
promising strategy to develop target-specific nanostructures. However, finding a chemical …

Surface functionalization of silica nanoparticles with cysteine: a low-fouling zwitterionic surface

JE Rosen, FX Gu - Langmuir, 2011 - ACS Publications
Herein, we report on the functionalization of silica nanoparticles with a small molecule, the
amino acid cysteine, in order to create a low-fouling zwitterionic surface for nanomedicine …

Tailoring pseudo-zwitterionic bifunctionalized silica nanoparticles: from colloidal stability to biological interactions

FR Scheffer, CP Silveira, J Morais, J Bettini… - Langmuir, 2020 - ACS Publications
Zwitterionic molecules are known to resist nonspecific protein adsorption and have been
proposed as an alternative to the widely used polyethylene glycol. Recently, zwitterionic-like …

pH-responsive silica coatings: a generic approach for smart protection of colloidal nanoparticles

M Lima, J Avó, MNMS Berberan-Santos… - ACS Applied Nano …, 2022 - ACS Publications
The silica coating of nanoparticles and of complex bioentities such as viruses has gathered
significant scientific interest due to the versatility of silica-based materials. These …

Highly flexible platform for tuning surface properties of silica nanoparticles and monitoring their biological interaction

I Ojea-Jiménez, P Urbán, F Barahona… - … Applied Materials & …, 2016 - ACS Publications
The following work presents a simple, reliable and scalable seeding-growth methodology to
prepare silica nanoparticles (SiO2 NPs)(20, 30, 50 and 80 nm) directly in aqueous phase …

Surface modification strategies on mesoporous silica nanoparticles for anti-biofouling zwitterionic film grafting

YL Khung, D Narducci - Advances in colloid and interface science, 2015 - Elsevier
In the past decade, zwitterionic-based anti-biofouling layers had gained much focus as a
serious alternative to traditional polyhydrophilic films such as PEG. In the area of assembling …

Biomimetic coating of gold nanoparticles with ultrathin silica layers

SM Kang, BS Lee, S Lee, IS Choi - Colloids and Surfaces A …, 2008 - Elsevier
Encapsulation of nanoparticles has attracted a great attention as a method for stabilizing
nanoparticles and subsequently applying them to various areas of technologies. Especially …

Short Zwitterionic Sulfobetaine-Modified Silica Nanoparticles: Is Neutrality Possible?

GB Mondo, M Cathcarth, GS Longo, AS Picco… - Langmuir, 2024 - ACS Publications
Zwitterionic coatings are an efficient strategy for preventing biomolecule adsorption and
enhancing nanoparticle stability in solution. The properties of zwitterions and other …

Tailored silica nanoparticles surface to increase drug load and enhance bactericidal response

LF Oliveira, K Bouchmella, AS Picco… - Journal of the Brazilian …, 2017 - SciELO Brasil
Nanoparticles' surface properties can be used as triggers to regulate or even enhance
biological response and generate tailored structures to substitute conventional antibiotics …

Silica nanoparticle applications in the biomedical field

LB Capeletti, LMD Loiola, AS Picco… - Smart Nanoparticles for …, 2018 - Elsevier
Abstract Silica nanoparticles (SiO 2 NPs) have been considered as promising platforms for
target-specific drug delivery. The large number of possible SiO 2 NP applications is based …