Inhibition of islet immunoreactivity by adiponectin is attenuated in human type 1 diabetes
TTL Pang, M Chimen, E Goble, N Dixon… - The Journal of …, 2013 - academic.oup.com
Context: Adiponectin is an adipocyte-derived cytokine with insulin-sensitizing and
antiinflammatory properties. These dual actions have not previously been examined in the …
antiinflammatory properties. These dual actions have not previously been examined in the …
Adiponectin is functionally active in human islets but does not affect insulin secretory function or β-cell lipoapoptosis
K Staiger, N Stefan, H Staiger… - The Journal of …, 2005 - academic.oup.com
Context: The adipokine adiponectin has insulin-sensitizing, antiatherogenic, and
antiinflammatory properties. Mouse and human adiponectin receptor-1 and-2 have been …
antiinflammatory properties. Mouse and human adiponectin receptor-1 and-2 have been …
The distribution of adiponectin receptors on human peripheral blood mononuclear cells
TTL Pang, P Narendran - Annals of the New York Academy of …, 2008 - Wiley Online Library
Adiponectin, an adipocytokine with anti‐inflammatory and insulin‐sensitizing properties,
may provide a mechanism by which insulin resistance accelerates autoimmunity in type 1 …
may provide a mechanism by which insulin resistance accelerates autoimmunity in type 1 …
Pro-inflammatory delipidizing cytokines reduce adiponectin secretion from human adipocytes without affecting adiponectin oligomerization
PJ Simons, PS van den Pangaart… - Journal of …, 2007 - joe.bioscientifica.com
Adiponectin and, especially, its oligomeric complex composition have been suggested to be
critical in determining insulin sensitivity. Pro-inflammatory cytokines play an important role in …
critical in determining insulin sensitivity. Pro-inflammatory cytokines play an important role in …
The multifaceted and controversial immunometabolic actions of adiponectin
S Esmaili, A Xu, J George - Trends in Endocrinology & Metabolism, 2014 - cell.com
Adiponectin, one of the most abundant adipose-derived hormones, has variable actions in
many tissues and organs. Although principally known for its insulin-sensitizing activity …
many tissues and organs. Although principally known for its insulin-sensitizing activity …
Regulation of adiponectin production by insulin: interactions with tumor necrosis factor-α and interleukin-6
T Hajri, H Tao, J Wattacheril… - American Journal …, 2011 - journals.physiology.org
Obesity is often associated with insulin resistance, low-grade systemic inflammation, and
reduced plasma adiponectin. Inflammation is also increased in adipose tissue, but it is not …
reduced plasma adiponectin. Inflammation is also increased in adipose tissue, but it is not …
Adiponectin and protection against type 2 diabetes mellitus
J Spranger, A Kroke, M Möhlig, MM Bergmann… - The Lancet, 2003 - thelancet.com
Adiponectin is an adipocyte-derived peptide, which has antiinflammatory and insulin-
sensitising properties. We designed a nested case-control study to assess whether baseline …
sensitising properties. We designed a nested case-control study to assess whether baseline …
Relationship between adiponectin and glycemic control, blood lipids, and inflammatory markers in men with type 2 diabetes
OBJECTIVE—Adiponectin, synthesized in the adipose tissue, appears to play an important
role in hyperglycemia and dyslipidemia, as well as in inflammatory mechanisms, which lead …
role in hyperglycemia and dyslipidemia, as well as in inflammatory mechanisms, which lead …
Adiponectin dysregulation and insulin resistance in type 1 diabetes
RI Pereira, JK Snell-Bergeon, C Erickson… - The Journal of …, 2012 - academic.oup.com
Context: Type 1 diabetes (T1D) is associated with insulin resistance despite elevated levels
of the insulin-sensitizing protein adiponectin. Whether the expected positive correlation …
of the insulin-sensitizing protein adiponectin. Whether the expected positive correlation …
The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity
LJ Martin, JG Woo, SR Daniels… - The Journal of …, 2005 - academic.oup.com
Context: Adipose tissue inflammation has been implicated in the pathogenesis of obesity-
related comorbidities. Adiponectin, an antiinflammatory protein, improves insulin sensitivity …
related comorbidities. Adiponectin, an antiinflammatory protein, improves insulin sensitivity …