A noninferiority randomized open-label pilot study of 3-versus 7-day influenza postexposure prophylaxis with oseltamivir in hospitalized children

A Wrotek, T Jackowska - Scientific Reports, 2024 - nature.com
Short influenza postexposure prophylaxis (PEP) showed high efficacy in adults, but studies
in children are lacking. This randomized open-label pilot trial aimed to verify noninferiority of …

Three-day regimen of oseltamivir for post-exposure prophylaxis of influenza in hospital wards: a study protocol for a prospective, multi-center, single-arm trial

N Ishiguro, YM Ito, S Iwasaki, M Nagao… - BMC Infectious …, 2021 - Springer
Background In a previous retrospective observational study, a 3-day regimen of oseltamivir
as post-exposure prophylaxis (PEP) for preventing transmission of influenza in wards was …

Five-day vs 10-day postexposure chemoprophylaxis with oseltamivir to prevent hospital transmission of influenza: a noninferiority randomized open-label study

L Lepen, R Blagus, M Velušček… - Open Forum …, 2020 - academic.oup.com
Background The efficacy and optimal duration of postexposure influenza prophylaxis with
oseltamivir are undetermined in hospital settings, where immediate separation from index …

Safety and tolerability of a 6‐week course of oseltamivir prophylaxis for seasonal influenza in children

K Reisinger, D Shu, L Cupelli… - Influenza and Other …, 2013 - Wiley Online Library
Please cite this paper as: Reisinger et al. Safety and tolerability of a 6‐week course of
oseltamivir prophylaxis for seasonal influenza in children. Influenza and Other Respiratory …

A prospective observational study of oseltamivir safety and tolerability in infants and young children≤ 24 months

BA Rath, WA Blumentals, MK Miller… - … and Drug Safety, 2015 - Wiley Online Library
Purpose Infants and young children are at elevated risk of influenza‐associated
complications, but information on the safety of antiviral therapies is limited in this age group …

Targeted antiviral prophylaxis with oseltamivir in a summer camp setting

DW Kimberlin, J Escude, J Gantner, J Ott… - … of pediatrics & …, 2010 - jamanetwork.com
Objective To describe the effectiveness of containment of novel influenza A (H1N1) infection
at a summer camp. Design Targeted use of oseltamivir phosphate by individuals in close …

Postexposure prophylaxis for influenza in pediatric wards oseltamivir or zanamivir after rapid antigen detection

M Shinjoh, Y Takano, T Takahashi… - The Pediatric …, 2012 - journals.lww.com
Background: Postexposure prophylaxis (PEP) using neuraminidase inhibitors against
exposure to influenza virus has been well studied in household settings but not in …

Association of early oseltamivir with improved outcomes in hospitalized children with influenza, 2007-2020

PS Walsh, D Schnadower, Y Zhang… - JAMA …, 2022 - jamanetwork.com
Importance Oseltamivir is recommended for all children hospitalized with influenza, despite
limited evidence supporting its use in the inpatient setting. Objective To determine whether …

Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review

RJ Jackson, KL Cooper, P Tappenden, A Rees… - Journal of Infection, 2011 - Elsevier
OBJECTIVE: To systematically review evidence relating to the clinical efficacy of oseltamivir,
zanamivir and amantadine in the prevention of influenza. METHODS: RCTs evaluating …

Systematic review: safety and efficacy of extended-duration antiviral chemoprophylaxis against pandemic and seasonal influenza

N Khazeni, DM Bravata, JEC Holty… - Annals of internal …, 2009 - acpjournals.org
Background: Neuraminidase inhibitors (NAIs) are stockpiled internationally for extended use
in an influenza pandemic. Purpose: To evaluate the safety and efficacy of extended-duration …