Purpose: To correlate the volume of lung irradiated with changes in plasma levels of the
fibrogenic cytokine transforming growth factor β (TGFβ) during radiotherapy (RT), such that …

PURPOSE: To test whether radiation-induced elevations of transforming growth factor-β1
(TGF-β1) during radiation therapy (RT) correlate with radiation-induced lung toxicity (RILT) …

Purpose: To determine whether plasma transforming growth factor-β (TGF-β) levels
measured before and during radical radiotherapy for lung cancer could be used to predict …

BACKGROUND: This study aimed to further investigate the role of circulating TGF-β1 during
radiation therapy (RT) in predicting radiation-induced lung toxicity (RILT). METHODS AND …

The maximum dose of radiation which can be delivered to a tumor is limited by the tolerance
of the surrounding normal tissues. The ability to identify patients at high or low risk of injury …

PURPOSE: In dose-escalation studies of radiotherapy (RT) for non–small-cell lung cancer
(NSCLC), radiation pneumonitis (RP) is the most important dose-limiting complication …

PURPOSE: To investigate the relevance of transforming growth factor-β (TGF-β) dynamics in
plasma for identification of patients at low risk for developing pneumonitis as a complication …

Purpose: To analyze plasma cytokine profiles before the initiation of radiation therapy to
define a cytokine phenotype that correlates with risk of developing symptomatic radiation …

Backgroud The underlying molecular and cellular mechanisms of radiation pneumonitis
(RP) are very complex. Several biological factors need to be considered together with the …

PURPOSE: To investigate the plasma dynamics of 5 proinflammatory/fibrogenic cytokines,
including interleukin-1beta (IL-1β), IL-6, IL-8, tumor necrosis factor alpha (TNF-α), and …