Abstract Epithelial-mesenchymal transition (EMT), a crucial step in disease progression,
plays a key role in tumor metastasis. N-cadherin, a well-known EMT marker, acts as a major …

Thyroid carcinoma is a common malignant tumor of endocrine system and head and neck.
Recurrence, metastasis and high malignant expression after routine treatment are serious …

Background: Recently, many studies have been carried out to investigate the
clinicopathological significance of E-cadherin expression in thyroid cancer. However, the …

The loss of E-cadherin and the gain of Ncadherin expression are known as “cadherin
switching”. Cadherin switching is a major hallmark of epithelialmesenchymal transition …

N-cadherin has been reported to be upregulated and associated with metastasis and poor
prognosis in prostate cancer patients, however the underlying mechanism still remains …

E-cadherin is a cell–cell adhesion protein and tumor suppressor that is silenced in many
malignancies. E-cadherin is thought to suppress tumor cell growth by antagonizing β …

Purpose: Deregulation of cell-to-cell adhesion molecules is a common and also critical
genetic event in epithelial malignancies leading to an increasing metastatic potential …

Junctional adhesion molecule A (JAM‐A) is a transmembrane protein that contributes to
different biological process, including the epithelial to mesenchymal transition (EMT) …

Tumor progression is characterized by loss of cell adhesion and increase of invasion and
metastasis. E-cadherin, a cell adhesion molecule, is frequently downregulated and has …

Background: Thyroid cancer (TC), the most common endocrine malignant tumor, is
increasingly causing a huge threat to our health nowadays. Methods: To explore the …