[HTML][HTML] Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord

J Hui, ZJ Zhang, X Zhang, Y Shen, YJ Gao - The Journal of Pain, 2013 - Elsevier
Hyperbaric oxygen (HBO) therapy is reported to attenuate pain in both clinical pain
conditions and animal pain models, but the underlying mechanism remains to be …

Hyperbaric oxygen treatment produces an antinociceptive response phase and inhibits astrocyte activation and inflammatory response in a rat model of neuropathic …

BS Zhao, LX Meng, YY Ding, YY Cao - Journal of Molecular Neuroscience, 2014 - Springer
Abstract Hyperbaric oxygen (HBO) treatment has been proven to be a promising candidate
for protection of the nervous system after acute injury in animal models of neuropathic pain …

Hyperbaric oxygen treatment decreases pain in two nerve injury models

CD Thompson, ML Uhelski, JR Wilson, PN Fuchs - Neuroscience research, 2010 - Elsevier
Hyperbaric oxygen (HBO) treatment has been used clinically to treat a variety of ailments,
including severe burns and carbon monoxide poisoning, and in research settings has …

[HTML][HTML] Hyperbaric oxygen treatment induces a 2-phase antinociceptive response of unusually long duration in mice

E Chung, LM Zelinski, Y Ohgami, DY Shirachi… - The journal of pain, 2010 - Elsevier
Hyperbaric oxygen (HBO2) therapy is approved by the FDA for limited clinical indications but
is reported to produce pain relief in several chronic pain conditions. However, there have …

Hyperbaric oxygen therapy attenuates neuropathic hyperalgesia in rats and idiopathic trigeminal neuralgia in patients

N Gu, JY Niu, WT Liu, YY Sun, S Liu, Y Lv… - … Journal of Pain, 2012 - Wiley Online Library
Background: Neuropathic pain after nerve injury is severe and intractable, and current drug
and non‐drug therapies offer very limited pain relief. Hyperbaric oxygen (HBO 2) has been …

Hyperbaric oxygen therapy: a new treatment for chronic pain?

AM Sutherland, HA Clarke, J Katz… - Pain Practice, 2016 - Wiley Online Library
Background and objective Hyperbaric oxygen therapy (HBOT) is a treatment providing
100% oxygen at a pressure greater than that at sea level. HBOT is becoming increasingly …

[HTML][HTML] Early hyperbaric oxygen effects on neuropathic pain and nitric oxide synthase isoforms in CCI rats

Y Ding, P Yao, T Hong, Z Han, B Zhao, W Chen… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Neuropathic pain is pain caused by injury or dysfunction in the central and/or peripheral
nervous system. Neuropathic pain has a high incidence with a complex mechanism, but …

Hyperbaric oxygen produces a nitric oxide synthase-regulated anti-allodynic effect in rats with paclitaxel-induced neuropathic pain

Y Zhang, AL Brewer, JT Nelson, PT Smith, DY Shirachi… - Brain research, 2019 - Elsevier
Research has demonstrated that hyperbaric oxygen (HBO 2) treatment produced relief of
both acute and chronic pain in patients and animal models. However, the mechanism of …

Effects of Hyperbaric Oxygen on Pain‐Related Behaviours and Nitric Oxide Synthase Expression in a Rat Model of Neuropathic Pain

G Han, L Li, L Meng - Pain Research and Management, 2013 - Wiley Online Library
BACKGROUND: Neuropathic pain is complex, and a satisfactory therapeutic method of
treatment has yet to be developed; therefore, finding a new and effective therapeutic method …

Mechanistic rationale and clinical efficacy of hyperbaric oxygen therapy in chronic neuropathic pain: an evidence‐based narrative review

S Schiavo, J DeBacker, C Djaiani… - Pain Research and …, 2021 - Wiley Online Library
Background. Chronic neuropathic pain is a condition affecting an increasing proportion of
the general population and its management requires a comprehensive, multidisciplinary …