The human cardiovascular system is exposed to plasma 5-hydroxytryptamine (5-HT,
serotonin), usually released from platelets. 5-HT can produce harmful acute and chronic …

All 5-hydroxytryptamine (5-HT; serotonin) receptors, except the 5-HT 6 type, have been
shown to be involved in cardiovascular regulation. In the periphery, 5-HT is stored in …

The effects of serotonin (5-hydroxytrypta-mine; 5-HT) on the cardiovascular system are
complex. These effects, consisting of bradycardia or tachycardia, hypotension or …

The complexity of cardiovascular responses produced by 5-hydroxytryptamine (5-HT,
serotonin), including bradycardia or tachycardia, hypotension or hypertension, and …

Study objective–The aim of the study was to investigate the receptor events that mediate the
vascular effects of 5-hydroxytryptamine (5-HT) on human coronary arteries, since 5-HT has …

5-Hydroxytryptamine (5-HT) can produce both vasoconstrictor and vasorelaxant effects in
human coronary arteries and the response to 5-HT can be influenced by the presence of …

The main peripheral sources of 5-hydroxytryptamine (5-HT) are as a neurotransmitter and
local hormone in the gastrointestinal tract, and stored in circulating platelets and pulmonary …

The pharmacological effects of 5-hydroxytryptamine (5-HT) on heart rate, arterial blood
pressure and urinary bladder pressure in the rat, and on the bronchi and ileum of the guinea …

We have investigated the ability of 5-hydroxytryptamine (5-HT) to elicit arrhythmic
contractions in isolated human atrial strips as a function of pacing rate (0.1–2 Hz) using a …

5-HT can potentially be released from aggregating platelets anywhere in the cardiovascular
system.'It can also be synthesised in neurones or be taken up by and released from …