The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most …

S Honda, N Misawa, Y Sato, D Oikawa… - Graefe's Archive for …, 2024 - Springer
Age-related macular degeneration (AMD) is the leading sight-threatening disease in
developed countries. On the other hand, recent studies indicated an ethnic variation in the …

[HTML][HTML] Association of genetic polymorphisms and age-related macular degeneration in Chinese population

J Tian, W Yu, X Qin, K Fang, Q Chen… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: We explored associations between age-related macular degeneration (AMD) and
genetic variants of 10 genes in a nationwide Chinese population. Methods.: In this …

Association of specific genetic polymorphisms with age-related macular degeneration in a northern Chinese population

W Zhuang, HP Li, Y Liu, J Zhao, S Ha, W Xiang… - Ophthalmic …, 2014 - Taylor & Francis
Purpose: The associations between genetic variants located in CFH, CFB, ARMS2 and
HTRA1 and the risk of age-related macular degeneration (AMD) in a northern Chinese …

The molecular genetic basis of age-related macular degeneration: an overview

S Katta, I Kaur, S Chakrabarti - Journal of genetics, 2009 - Springer
Age-related macular degeneration (AMD) is a complex disorder of the eye and the third
leading cause of blindness worldwide. With a multifactorial etiology, AMD results in …

[HTML][HTML] Association of ARMS2, HTRA1 and CFH genes polymorphisms in patients with age-related macular degeneration in the Malaysian population

F Ismail, SM Junit, LC Chin, JJ Jayapalan… - Egyptian Journal of …, 2024 - Springer
Background Despite extensive research efforts, understanding the precise causes and
molecular underpinnings of age-related macular degeneration (AMD) remains elusive …

Genomic aspects of age-related macular degeneration

K Horie-Inoue, S Inoue - Biochemical and biophysical research …, 2014 - Elsevier
Age-related macular degeneration (AMD) is a major late-onset posterior eye disease that
causes central vision to deteriorate among elderly populations. The predominant lesion of …

Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population

CHU Jie, C Zhou, LU Ning, X Zhang… - Chinese medical …, 2008 - journals.lww.com
Background The present study was undertaken to replicate the associations of
representative polymorphisms in three genes (complement factor H (CFH), complement …

Age-related macular degeneration-susceptibility single nucleotide polymorphisms in a han chinese control population

J Hu, Y Yuan, L Shen, J Zhang, N Hu… - Ophthalmic …, 2011 - Taylor & Francis
Purpose: Our study aimed to detect the frequency of age-related macular degeneration
(AMD)-susceptibility single nucleotide polymorphisms (SNPs) in control subjects of Han …

[HTML][HTML] Comparison of risk allele frequencies of single nucleotide polymorphisms associated with age-related macular degeneration in different ethnic groups

HT Shin, BW Yoon, JH Seo - BMC ophthalmology, 2021 - Springer
Background The prevalence of age-related macular degeneration (AMD) varies from 6.8 to
18.3% for all forms of AMD and from 0.6 to 2.6% for late AMD according to race, suggesting …

[HTML][HTML] Age-related macular degeneration: genome-wide association studies to translation

JRM Black, SJ Clark - Genetics in Medicine, 2016 - Elsevier
In recent years, genome-wide association studies (GWAS), which are able to analyze the
contribution to disease of genetic variations that are common within a population, have …