Graphene oxide as antibacterial sensitizer: Mechanically disturbed cell membrane for enhanced poration efficiency of melittin

S Xiao, X Lu, L Gou, J Li, Y Ma, J Liu, K Yang, B Yuan - Carbon, 2019 - Elsevier
Natural antimicrobial peptides (AMPs) promise a fundamental solution to the devastating
threat of multidrug-resistant bacteria, while drawbacks such as limited antibacterial efficiency …

Designing melittin‐graphene hybrid complexes for enhanced antibacterial activity

X Lu, J Liu, L Gou, J Li, B Yuan… - Advanced healthcare …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs) promise a fundamental solution to the devastating threat of
drug‐resistant bacteria. However, drawbacks of AMPs (eg, poor cell membrane penetration …

Antimicrobial peptide-conjugated graphene oxide membrane for efficient removal and effective killing of multiple drug resistant bacteria

R Kanchanapally, BPV Nellore, SS Sinha, F Pedraza… - RSC …, 2015 - pubs.rsc.org
According to the World Health Organization (WHO), multiple drug-resistant (MDR) bacterial
infection is a top threat to human health. Since bacteria evolve to resist antibiotics faster than …

Interaction of graphene and its oxide with lipid membrane: a molecular dynamics simulation study

J Chen, G Zhou, L Chen, Y Wang… - The Journal of …, 2016 - ACS Publications
Graphene nanosheet has exhibited an increasing prospect in various biomedical
applications because of its extraordinary properties. Meanwhile, recent experiments have …

Understanding the sheet size-antibacterial activity relationship of graphene oxide and the nano-bio interaction-based physical mechanisms

CH Yu, GY Chen, MY Xia, Y Xie, YQ Chi, ZY He… - Colloids and Surfaces B …, 2020 - Elsevier
The antibiotics-independent antimicrobial activity of graphene oxide (GO) is of great
importance since antibiotic therapy is facing great challenges from drug resistance …

Bacteria meet graphene: modulation of graphene oxide nanosheet interaction with human pathogens for effective antimicrobial therapy

V Palmieri, F Bugli, MC Lauriola, M Cacaci… - ACS Biomaterials …, 2017 - ACS Publications
The development of new pharmacological strategies that evade bacterial resistance has
become a compelling worldwide challenge. Graphene oxide (GO) can represent the …

Synthetic peptide (DP1) functionalized graphene oxide: A biocompatible nanoformulation with broad-spectrum antibacterial and antibiofilm activity

S Joshi, J Chadha, K Harjai, G Verma, A Saini - FlatChem, 2024 - Elsevier
In the present scenario, clinical success of all existing antimicrobial regimes has been
severely challenged by bacterial infections and emergence of multidrug-resistant strains …

Graphene oxide with acid-activated bacterial membrane anchoring for improving synergistic antibacterial performances

S Huo, Y Gao, L Fang, Z Jiang, Q Xie, Q Meng… - Applied Surface …, 2021 - Elsevier
Bacterial resistance toward antibiotics has become a major threat to current anti-infective
therapy, and now it's very urgent to develop new therapeutic drugs and coping strategies for …

[HTML][HTML] Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment

F De Maio, V Palmieri, A Salustri, G Perini… - Nanoscale …, 2019 - pubs.rsc.org
Tuberculosis (TB) remains a global threat and there is an urgent need for improved drugs
and treatments, particularly against the drug-resistant strains of Mycobacterium tuberculosis …

Molecular dynamics studies on the bacterial membrane pore formation by small molecule antimicrobial agents

FA Daison, N Kumar, S Balakrishnan… - Journal of Chemical …, 2021 - ACS Publications
Antimicrobial peptides (AMPs) act on the membrane bilayer of pathogens, causing leakage
in the membrane and cell death. Amphiphilic kaempferol derivatives possessing basic …