Oncolytic virotherapy is a promising immunotherapy approach for cancer treatment that
utilizes viruses to preferentially infect and eliminate cancer cells while stimulating the …

Background: The use of oncolytic viruses for treatment of cancer marks a significant
alteration in the battle between host and virus. Viruses are confronted by cellular innate …

Oncolytic viruses (OVs), above and beyond infecting and lysing malignant cells, interact with
the immune system in complex ways that have important therapeutic significance. While …

Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for
patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells …

The imbalance of immune response plays a crucial role in the development of diseases,
including glioblastoma. It is essential to comprehend how the innate immune system detects …

Highlights•Oncolytic viral therapy triggers a number of host responses including anti-viral
and anti-tumor responses.•Increasing evidence suggests that both facets of the immune …

Oncolytic virus (OV) therapy is a promising cancer treatment strategy, which selectively
replicates in and destroys tumor cells rather than normal cells, thereby effectively releasing …

Oncolytic viruses are novel anticancer agents that have been increasingly employed as key
components of therapeutic regimens. Recently, the field of viroimmunotherapy has …

Oncolytic viruses (OVs), viruses engineered to lyse tumor cells, work hand in hand with the
immune response. While for decades the field isolated lytic capability and viral spread to …

Oncolytic viruses (OVs) constitute a new and promising immunotherapeutic approach
toward cancer treatment. This therapy takes advantage of the natural propensity of most …