Diabetic nephropathy (DN) is a major life-threatening complication of diabetes. Renal
lesions affect glomeruli and tubules, but the pathogenesis is not completely understood …

Although several factors may mediate the development and progression of diabetic
nephropathy, hyperlipidemia is now considered an independent and major determinant of …

Metabolic changes associated with diabetes are reported to lead to the onset of early-stage
diabetic nephropathy (DN). Furthermore, lipotoxicity is implicated in renal dysfunction. Most …

Studies of renal injury III: Lipid-induced nephropathy in type II diabetes Background
Nephrotoxicity from elevated circulating lipids occurs in experimental and clinical situations …

Role of lipid control in diabetic nephropathy. Patients with diabetic nephropathy are known
to be associated with many lipoprotein abnormalities, including higher plasma levels of very …

Although diabetes is mainly diagnosed based on elevated glucose levels, dyslipidemia is
also observed in these patients. Chronic kidney disease (CKD), a frequent occurrence in …

Glycosphingolipids (GSLs) play a role in insulin resistance and diabetes, but their role in
diabetic nephropathy (DN) has received limited attention. We used 9-and 17-wk-old …

One of the central functions of the kidney is to excrete low molecular weight, water soluble,
plasma, waste products into the urine, whereas macromolecules, the size of albumin and …

Diabetic nephropathy is an increasingly important cause of morbidity and mortality
worldwide. A large body of evidence suggests that dyslipidemia has an important role in the …

Dyslipoproteinemia in non-insulin-dependent diabetes mellitus (NIDDM) is an important risk
factor in the development of atherosclerosis and glomerulosclerosis. The lipid profile of …