Dietary restriction promotes resistance to surgical stress in multiple organisms.
Counterintuitively, current medical protocols recommend short-term carbohydrate-rich drinks …

Dietary restriction (DR) is best known for extending lifespan in experimental model
organisms, but also increases resistance to a variety of clinically relevant stressors …

Dietary restriction, or reduced food intake without malnutrition, increases life span, health
span, and acute stress resistance in model organisms from yeast to nonhuman primates …

Sickness behaviors, including anorexia, are evolutionarily conserved responses to acute
infections. Inflammation-induced anorexia causes dramatic metabolic changes, of which …

Surgery and traumatic injury set off a cascade of metabolic changes that are becoming
better understood. Recently, strategies and protocols have been developed for optimizing …

Background Intestinal ischaemia/reperfusion (I/R) injury is a grave surgical event with high
morbidity and mortality. Preoperative fasting might confer protection against intestinal I/R …

BACKGROUND: Short-term changes in preoperative nutrition can have profound effects on
surgery-related outcomes such as ischemia/reperfusion injury in preclinical models. Dietary …

Objective The mechanisms by which bariatric surgeries so effectively and lastingly reduce
body weight and normalize metabolic dysfunction are not well understood. Fibroblast growth …

Chronic exposure to high-fat diets (HFD) worsens intestinal disease pathology, but acute
effects of HFD in tissue damage remain unclear. Here, we used short-term HFD feeding in a …

The liver plays a crucial role in mobilizing energy during nutritional deprivation. During the
early stages of fasting, hepatic glycogenolysis is a primary energy source. As fasting …