Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
FM LaFerla - Nature Reviews Neuroscience, 2002 - nature.com
Calcium modulates many neural processes, including synaptic plasticity and apoptosis.
Dysregulation of intracellular calcium signalling has been implicated in the pathogenesis of …
Dysregulation of intracellular calcium signalling has been implicated in the pathogenesis of …
Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities
JT Yu, RCC Chang, L Tan - Progress in neurobiology, 2009 - Elsevier
Calcium is involved in many facets of neuronal physiology, including activity, growth and
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …
Neuronal and glial calcium signaling in Alzheimer's disease
MP Mattson, SL Chan - Cell calcium, 2003 - Elsevier
Cognitive impairment and emotional disturbances in Alzheimer's disease (AD) result from
the degeneration of synapses and death of neurons in the limbic system and associated …
the degeneration of synapses and death of neurons in the limbic system and associated …
The dysregulation of intracellular calcium in Alzheimer disease
C Supnet, I Bezprozvanny - Cell calcium, 2010 - Elsevier
Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …
Intracellular calcium dysregulation: implications for Alzheimer's disease
S Magi, P Castaldo, ML Macrì… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
The pathogenesis of Alzheimers disease—is it a lifelong “Calciumopathy”?
GE Stutzmann - The Neuroscientist, 2007 - journals.sagepub.com
Alzheimer's disease (AD) is a fatal neurodegenerative disorder that has no known cure, nor
is there a clear mechanistic understanding of the disease process itself. Although amyloid …
is there a clear mechanistic understanding of the disease process itself. Although amyloid …
[HTML][HTML] Calcium signaling in Alzheimer's disease & therapies
Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
Calcium channelopathies and Alzheimer's disease: insight into therapeutic success and failures
S Chakroborty, GE Stutzmann - European journal of pharmacology, 2014 - Elsevier
Calcium ions are versatile and universal biological signaling factors that regulate numerous
cellular processes ranging from cell fertilization, to neuronal plasticity that underlies learning …
cellular processes ranging from cell fertilization, to neuronal plasticity that underlies learning …
Calcium dyshomeostasis in Alzheimer's disease pathogenesis
R Cascella, C Cecchi - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
[HTML][HTML] Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease
S Camandola, MP Mattson - … et Biophysica Acta (BBA)-Molecular Cell …, 2011 - Elsevier
In this mini-review/opinion article we describe evidence that multiple cellular and molecular
alterations in Alzheimer's disease (AD) pathogenesis involve perturbed cellular calcium …
alterations in Alzheimer's disease (AD) pathogenesis involve perturbed cellular calcium …
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