Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate rat hepatic ischemia‐reperfusion injury by suppressing oxidative stress …

J Yao, J Zheng, J Cai, K Zeng, C Zhou… - The FASEB …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been reported to exert therapeutic effects on
immunoregulation, tissue repair, and regeneration from the bench to the bedside. Increasing …

Extracellular vesicles derived from human umbilical cord mesenchymal stem cells protect liver ischemia/reperfusion injury by reducing CD154 expression on CD4+ T …

J Zheng, T Lu, C Zhou, J Cai, X Zhang… - Advanced …, 2020 - Wiley Online Library
As a cause of postoperative complications and early hepatic failure after liver
transplantation, liver ischemia/reperfusion injury (IRI) still has no effective treatment during …

Extracellular vesicles derived from mesenchymal stromal cells as nanotherapeutics for liver ischaemia–reperfusion injury by transferring mitochondria to modulate the …

T Lu, J Zhang, J Cai, J Xiao, X Sui, X Yuan, R Li, Y Li… - Biomaterials, 2022 - Elsevier
As nanotherapeutics, mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs)
are considered a potent alternative for whole-cell therapy and are gradually entering the …

[PDF][PDF] Extracellular vesicles from bone marrow–derived mesenchymal stem cells protect against murine hepatic ischemia/reperfusion injury

H Haga, IK Yan, DA Borrelli, A Matsuda… - Liver …, 2017 - Wiley Online Library
Hepatic ischemia/reperfusion injury (IRI) and associated inflammation contributes to liver
dysfunction and complications after liver surgery and transplantation. Mesenchymal stem …

Human mesenchymal stromal cell-derived extracellular vesicles improve liver regeneration after ischemia reperfusion injury in mice

F Anger, M Camara, E Ellinger, CT Germer… - Stem Cells and …, 2019 - liebertpub.com
Hepatic ischemia reperfusion injury (IRI) remains a major obstacle in liver resection and
transplantation surgery, especially in diseased organs. Human mesenchymal stromal cells …

Human Umbilical Cord MSC‐Derived Exosomes Suppress the Development of CCl4‐Induced Liver Injury through Antioxidant Effect

W Jiang, Y Tan, M Cai, T Zhao, F Mao… - Stem cells …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been increasingly applied into clinical therapy.
Exosomes are small (30–100 nm in diameter) membrane vesicles released by different cell …

Exosomal miR‐1246 derived from human umbilical cord blood mesenchymal stem cells attenuates hepatic ischemia reperfusion injury by modulating T helper 17 …

K Xie, L Liu, J Chen, F Liu - IUBMB life, 2019 - Wiley Online Library
The purpose of this study was to explore the mechanism by which human umbilical cord
blood mesenchymal stem cells (hUCB‐MSCs)‐derived exosomes exerted protective effect …

Exosomes derived from human umbilical cord blood mesenchymal stem cells improve hepatic ischemia reperfusion injury via delivering miR-1246

K Xie, L Liu, J Chen, F Liu - Cell Cycle, 2019 - Taylor & Francis
The purpose of this study was to explore the associated mechanism by which MSCs-derived
exosomes exerted protective effect in hepatic ischemia/reperfusion injury (IRI). Human …

MiR‐20a‐containing exosomes from umbilical cord mesenchymal stem cells alleviates liver ischemia/reperfusion injury

L Zhang, Y Song, L Chen, D Li, H Feng… - Journal of cellular …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been proved to exert considerable therapeutic effects
on ischemia‐reperfusion (I/R)‐induced injury, but the underlying mechanism remains …

Extracellular vesicles from bone marrow-derived mesenchymal stem cells improve survival from lethal hepatic failure in mice

H Haga, IK Yan, K Takahashi… - Stem cells …, 2017 - academic.oup.com
Stem cell-based therapies have potential for treatment of liver injury by contributing to
regenerative responses, through functional tissue replacement or paracrine effects. The …