We report the first direct electrochemical characterization of the impact of oxygen on the
hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase …

Hydrogenases are essential for H2 cycling in microbial metabolism and serve as valuable
blueprints for H2-based biotechnological applications. However, most hydrogenases are …

The catalytic properties of hydrogenases are nature's answer to the seemingly simple
reaction H2⇌ 2H++ 2e–. Members of the phylogenetically diverse subgroup of [NiFe] …

Abstract 'Oxygen-tolerant'[NiFe]-hydrogenases can catalyze H 2 oxidation under aerobic
conditions, avoiding oxygenation and destruction of the active site. In one mechanism …

An important clue to the mechanism for O2 tolerance of certain [NiFe]-hydrogenases is the
conserved presence of a modified environment around the iron–sulfur cluster that is …

Group 1 hydrogenases are periplasmic enzymes and are thus strongly affected by the
“outside world” the cell experiences. This exposure has brought about an extensive …

Hydrogenases are efficient biological catalysts of H2 oxidation and production. Most of them
are inhibited by O2, and a prerequisite for their use in biotechnological applications under …

The bacterial [NiFe]-hydrogenases have been classified as either 'standard'or 'O2-
tolerant'based on their ability to function in the presence of O2. Typically, these enzymes …

An oxygen-tolerant respiratory [NiFe]-hydrogenase is proven to be a four-electron
hydrogen/oxygen oxidoreductase, catalyzing the reaction 2 H2+ O2= 2 H2O, equivalent to …

Characterizing a new hydrogenase: The newly isolated [NiFeSe] hydrogenase from
Desulfovibrio vulgaris Miyazaki F displays catalytic properties distinct from other …