Rationale: Studies demonstrating early structural lung damage in infants and preschool
children with cystic fibrosis (CF) suggest that noninvasive monitoring will be important to …

Rationale: Recent advancements that have been made in magnetic resonance imaging
(MRI) improve our ability to assess pulmonary structure and function in patients with cystic …

Rationale: Early onset and progression of lung disease in children with cystic fibrosis (CF)
indicates that sensitive noninvasive outcome measures are needed for diagnostic …

Rationale: Previous cross-sectional studies have demonstrated that chest magnetic
resonance imaging (MRI) is sensitive to detect early lung disease in infants and preschool …

Computed tomography (CT) is the current “gold standard” for assessment of lung
morphology and is so far the most reliable imaging modality for monitoring cystic fibrosis …

Background A recent single-centre study demonstrated that MRI is sensitive to detect early
abnormalities in the lung and response to therapy in infants and preschool children with …

Lung function tests are commonly used to monitor lung disease in cystic fibrosis (CF). While
practical, they cannot locate the exact origin of functional impairment. Contemporary …

Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

In cystic fibrosis (CF) patients, both severe lung inflammation and severe lung damage occur
early and persist throughout life. High‐resolution computed tomography (HRCT), a more …

To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest
MRI has been historically out of the scope of routine clinical imaging due to technical …