Objectives To identify genes that may play a role in urethral stricture and summarize the
results of studies that have documented variations in gene expression among individuals …

Urethral fibrosis is an important pathological feature of urethral stricture. TGF-β1 and CXC
chemokine receptor 3 (CXCR3) signaling have been reported as the critical pathways …

Objective The contribution of genetic factors to the presence of an overactive bladder is
recognized. This study aimed to (1) assemble and synthesize available data from studies …

Introduction A contribution of genetic factors to the development of stress urinary
incontinence (SUI) is broadly acknowledged. This study aimed to:(1) provide insight into the …

Aim To elucidate the precise cellular and molecular mechanisms that underlie urethral
fibrogenesis. Methods Endoluminal electrocautery injury (using Karl Storz 10 Fr. Pediatric …

Purpose: Genome-wide association studies have not identified replicable genetic risk loci for
stress or urgency urinary incontinence. Materials and Methods: We carried out a discovery …

Background: Urethral stricture is a common disorder of the lower urinary tract in men. A
complex network of pathways and interactions are involved in the pathogenesis of urethral …

Urethral stricture disease is relatively common and is associated with a significant financial
cost and potentially debilitating outcomes. Understanding urethral stricture epidemiology is …

Background The pathogenesis of urolithiasis is multi-factorial and genetic factors have been
shown to play a significant role in the development of urolithiasis. We tried to apply genome …

Stress urinary incontinence (SUI) is a common and burdensome condition. Because of the
large knowledge gap around the molecular processes involved in its pathophysiology, the …