Background: Although observational studies have demonstrated that blood lipids are
associated with female infertility, the causality of this association remains unclear. We …

Objective: Observational studies have linked lifestyle, diet, obesity, and biochemical
measures with infertility. Whether this association is causal is unclear. We sought to identify …

Study question Is the risk of endometriosis associated with genetically predicted levels of
different blood lipid and apolipoprotein traits? Summary answer Our Mendelian …

Background The intrauterine environment is critical for fetal growth and development.
However, observational associations between maternal gestational lipid concentrations and …

Single nucleotide polymorphisms (SNPs) represent genetic variations among individuals in
a population. In medicine, these small variations in the DNA sequence may significantly …

Context: A role of lipids in human fecundity is hypothesized as cholesterol is the main
substrate for steroid synthesis and has also been shown to affect the hormonal milieu and …

STUDY QUESTION Are maternal preconception lipid levels associated with fecundability?
SUMMARY ANSWER Fecundability was reduced for all abnormal female lipid levels …

Ovarian cancer (OC), and particularly epithelial OC (EOC), is an increasing challenge for
women. Circulating lipids play different roles in the occurrence and development of OC, but …

Background This study investigates the causal relationship between lipid traits and GDM in
an effort to better understand the aetiology of GDM. Methods Employing a two-sample …

Research question Is a mixture of preconception serum lipids and lipophilic micronutrients
associated with clinical pregnancy and live births? Design In this prospective cohort study …