[HTML][HTML] Functional characterization of the dural sinuses as a neuroimmune interface
Despite the established dogma of central nervous system (CNS) immune privilege,
neuroimmune interactions play an active role in diverse neurological disorders. However …
neuroimmune interactions play an active role in diverse neurological disorders. However …
Advances in meningeal immunity
R Rua, DB McGavern - Trends in molecular medicine, 2018 - cell.com
The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …
The CNS immune landscape from the viewpoint of a T cell
Neuro-immune interactions are not only vital for the control of neurotropic pathogens, but
also appear to influence brain development and homeostasis. During immune surveillance …
also appear to influence brain development and homeostasis. During immune surveillance …
Distinct roles of the meningeal layers in CNS autoimmunity
A Merlini, M Haberl, J Strauß, L Hildebrand… - Nature …, 2022 - nature.com
The meninges, comprising the leptomeninges (pia and arachnoid layers) and the
pachymeninx (dura layer), participate in central nervous system (CNS) autoimmunity, but …
pachymeninx (dura layer), participate in central nervous system (CNS) autoimmunity, but …
Revisiting the mechanisms of CNS immune privilege
Whereas the study of the interactions between the immune system and the central nervous
system (CNS) has often focused on pathological conditions, the importance of neuroimmune …
system (CNS) has often focused on pathological conditions, the importance of neuroimmune …
[HTML][HTML] Meningeal tertiary lymphoid tissues and multiple sclerosis: a gathering place for diverse types of immune cells during CNS autoimmunity
Collections of leukocytes in the meningeal space have been documented in Multiple
Sclerosis (MS). These meningeal aggregates, which in the context of other autoimmune …
Sclerosis (MS). These meningeal aggregates, which in the context of other autoimmune …
The meninges: new therapeutic targets for multiple sclerosis
AE Russi, MA Brown - Translational Research, 2015 - Elsevier
The central nervous system (CNS) largely comprises nonregenerating cells, including
neurons and myelin-producing oligodendrocytes, which are particularly vulnerable to …
neurons and myelin-producing oligodendrocytes, which are particularly vulnerable to …
Immune dynamics in the CNS and its barriers during homeostasis and disease
MW Buckley, DB McGavern - Immunological reviews, 2022 - Wiley Online Library
The central nervous system (CNS) has historically been viewed as an immunologically
privileged site, but recent studies have uncovered a vast landscape of immune cells that …
privileged site, but recent studies have uncovered a vast landscape of immune cells that …
Multifaceted interactions between adaptive immunity and the central nervous system
J Kipnis - Science, 2016 - science.org
Neuroimmunologists seek to understand the interactions between the central nervous
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
The anatomical and cellular basis of immune surveillance in the central nervous system
RM Ransohoff, B Engelhardt - Nature Reviews Immunology, 2012 - nature.com
The central nervous system (CNS) comprises the brain, spinal cord, optic nerves and retina,
and contains post-mitotic, delicate cells. As the rigid coverings of the CNS render swelling …
and contains post-mitotic, delicate cells. As the rigid coverings of the CNS render swelling …