The most common type of lung cancer is adenocarcinoma (ADC), comprising around 40% of
all lung cancer cases. In spite of achievements in understanding the pathogenesis of this …

The adenocarcinoma of the lung has recently shown peculiar molecular characteristics,
which relate with both carcinogenesis and response to targeted drugs. Several molecular …

Lung cancer is a devastating disease with a poor prognosis. Non-small cell lung cancer
(NSCLC) and small cell lung cancer (SCLC) represent different forms of lung cancer that are …

Although adenocarcinoma (ADC) is the most frequent lung cancer, its diagnosis is often late,
when the local invasion is important and/or the metastases have already appeared …

Lung adenocarcinoma (LADC) is a cancer treatable using targeted therapies against driver
gene aberrations. EGFR mutations and ALK fusions are frequent gene aberrations in LADC …

Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …

In recent years, there have been multiple breakthroughs in our understanding of lung cancer
biology. Despite significant advances in molecular targeted therapies, DNA-damaging …

Historically, the prognosis for individuals diagnosed with lung cancer has been bleak.
However, the past 10 years have seen important advances in treatment and diagnosis which …

Lung cancer is the leading cause of cancer death worldwide. The disease is particularly
difficult to detect, and patients often present at an advanced stage. Current treatments have …

The past decade has been transformative for lung cancer patients, physicians, and
scientists. The discovery of EGFR mutations that confer sensitivity to tyrosine kinase …