Normal hypothalamopituitary development is closely related to that of the forebrain and is
dependent upon a complex genetic cascade of transcription factors and signaling molecules …

The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis.
The development of the pituitary gland depends on the sequential temporal and spatial …

Context Congenital hypopituitarism (CH) is characterized by the presence of deficiencies in
one or more of the 6 anterior pituitary (AP) hormones secreted from the 5 different …

Defects in pituitary gland organogenesis are sometimes associated with congenital
anomalies that affect head development. Lesions in transcription factors and signaling …

The pituitary gland functions as a relay between the hypothalamus and peripheral target
organs that regulate basic physiological functions, including growth, the stress response …

Pituitary gland commitment from oral ectoderm occurs in response to inductive signals from
the neuroepithelium of the ventral diencephalon. Invagination of the oral ectoderm leads to …

The pituitary gland is a complex organ secreting six hormones from five different cell types. It
is the end product of a carefully orchestrated pattern of expression of signalling molecules …

The embryonic development of the pituitary gland involves a complex and highly spatio-
temporally regulated network of integrating signalling molecules and transcription factors …

The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis,
and is the end-product of a carefully orchestrated pattern of expression of signalling …

The past 12 years have witnessed an explosion in our understanding of the development of
the anterior pituitary gland, and of mechanisms that underlie the diagnosis of growth …