MiRNAs and cancer: key link in diagnosis and therapy

Y Shi, Z Liu, Q Lin, Q Luo, Y Cen, J Li, X Fang, C Gong - Genes, 2021 - mdpi.com
Since the discovery of the first microRNA (miRNA), the exploration of miRNA biology has
come to a new era in recent decades. Monumental studies have proven that miRNAs can be …

The role of miRNAs in cancer: from pathogenesis to therapeutic implications

M Seven, OF Karatas, MB Duz, M Ozen - Future oncology, 2014 - Future Medicine
Cancer is still one of the dominating causes of deaths worldwide, although there have been
important enhancements for detection and diagnosis of cancer recently. miRNAs are shown …

Recent trends in targeting miRNAs for cancer therapy

V Shah, J Shah - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …

MicroRNAs: novel players in cancer diagnosis and therapies

AL Oom, BA Humphries, C Yang - BioMed research …, 2014 - Wiley Online Library
First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas
over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in …

MiRNA-based therapeutic intervention of cancer

S Naidu, P Magee, M Garofalo - Journal of hematology & oncology, 2015 - Springer
MicroRNAs (miRNAs) are important modulators of eukaryotic gene expression. By targeting
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …

[HTML][HTML] MicroRNA as an important target for anticancer drug development

Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

Therapeutic targeting of microRNAs in cancer: future perspectives

L Tutar, E Tutar, A Özgür, Y Tutar - Drug development research, 2015 - Wiley Online Library
ABSTRACT Preclinical Research The discovery of microRNAs (miRNAs) and their link with
cancer has opened a new era in cancer therapeutics. Approximately, 18− 24 nucleotides …

miRNAs and their potential for use against cancer and other diseases

E Tili, JJ Michaille, V Gandhi, W Plunkett, D Sampath… - 2007 - Future Medicine
miRNAs are 19–24 nucleotide long noncoding RNAs found in almost all genetically
dissected species, including viruses, plants, nematodes, flies, fish, mice and humans. Rapid …

microRNA therapeutics in cancer—an emerging concept

MY Shah, A Ferrajoli, AK Sood, G Lopez-Berestein… - …, 2016 - thelancet.com
MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …

Exploring miRNA based approaches in cancer diagnostics and therapeutics

S Mishra, T Yadav, V Rani - Critical reviews in oncology/hematology, 2016 - Elsevier
MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …