STUDY QUESTION What is the long-term reproductive health outcome of patients who have
undergone testicular sampling for fertility preservation (FP) before and during the pubertal …

Background Few studies have reported the long‐term outcomes of prepubertal and pubertal
boys undergoing testicular biopsy for fertility preservation (FP). Procedure This prospective …

STUDY QUESTION Is testicular growth affected by a testicular biopsy intended for fertility
preservation in pre-pubertal boys with cancer? SUMMARY ANSWER Testicular growth of …

Background: A multi-disciplinary approach has led to an improvement in prognosis of
childhood cancers. However, in parallel with the increase in survival rate, there is a greater …

No consensus exists regarding the precise role of testicular biopsy in prepubertal boys,
although it is considered useful for assessing the potential consequences of undescended …

STUDY QUESTION Does chemotherapy exposure (with or without alkylating agents) or
primary diagnosis affect spermatogonial quantity in human prepubertal testicular tissue …

The introduction of ICSI has totally changed the reproductive prospects for boys and men
who are treated for cancer. With post-pubertal boys and adult men, semen cryopreservation …

Background Advances in cancer treatment have led to improved long‐term survival after
childhood cancer, but often at a price of impaired future fertility. Fertility preservation (FP) in …

Patient survival following childhood cancer has increased with contemporary radiation and
chemotherapy techniques. However, gonadotoxicity associated with treatments means that …

Purpose: Cryopreservation of testicular tissue with subsequent reimplantation after therapy
has the potential to preserve fertility for prepubertal boys with cancer. We present the …