Leishmaniasis remains a significant global health concern, with current treatments relying
on outdated drugs associated with high toxicity, lengthy administration, elevated costs, and …

Leishmaniasis remains one of the main public health problems worldwide, with special
incidence in the poorest populations. Selenium and its derivatives can be potent therapeutic …

Nowadays, leishmaniasis is still treated with outdated drugs that present several obstacles
related to their high toxicity, long duration, parenteral administration, high costs and drug …

Leishmaniasis is an endemic disease caused by obligate intracellular protozoa of the genus
Leishmania prevalent in the Americas, Africa, and Asia. Therapeutic options are limited for …

Diselenide and sulfonamide derivatives have recently attracted considerable interest as
leishmanicidal agents in drug discovery. In this study, a novel series of sixteen hybrid …

Compounds 1 and 2 (selenocyanate and diselenide derivatives, respectively) were
evaluated for their potential use in vivo against visceral leishmaniasis (VL). Both entities …

ABSTRACT A series of new selenocyanates and diselenides bearing interesting bioactive
scaffolds (quinoline, quinoxaline, acridine, chromene, furane, isosazole, etc.) was …

This study describes a virtual screening performed for two series of selenides (28
compounds), derived from N-phenylacetamides chlorides and 7-chloro-quinoline, to …

The in vitro leishmanicidal activities of a series of 48 recently synthesized selenium
derivatives against Leishmania infantum and Leishmania braziliensis parasites were tested …

Leishmaniasis is a neglected tropical disease and a public health concern in at least 98
countries, affecting mainly the poorest populations. Pharmaceuticals and chemotherapies …