Researchers have found considerable evidence in the past 20 years that perinatal opioid
exposure leads to an increased risk of developmental disorders in offspring that persist into …

The long-term consequences of perinatal opioid exposure and subsequent development of
neonatal opioid withdrawal syndrome is largely unknown and likely dependent on a …

Neonatal opioid withdrawal syndrome (NOWS) has risen in prevalence from 1.2 per 1000
births in 2000 to 5.8 per 1000 births in 2012. Symptoms in neonates may include high …

Prenatal opioid exposure has reached epidemic proportions. In the last 10 years, there has
been a 242% increase in the number of babies born with the drug withdrawal syndrome …

Neonatal opioid withdrawal syndrome (NOWS) is a growing public health concern. The
complexity of in utero opioid exposure in clinical studies makes it difficult to investigate …

The overall prevalence of opiate use has been increasing, currently affecting approximately
0.6% of the global population and resulting in a significant proportion of infants being born …

The opioid epidemic has adversely affected neonates and children, yet the mechanisms by
which it impacts this population are not well understood. Not only does prenatal opioid …

Background Prenatal opioid exposure has been associated with developmental deficits
during infancy, but the literature is limited by simple group comparisons and lack of …

Substance abuse and the ongoing opioid epidemic represents a large societal burden. This
review will consider the long-term impact of opioid exposure on future generations. Prenatal …

Opioid use during pregnancy impacts the health and well‐being of two generations: the
pregnant person and the child. The factors that increase risk for opioid use in the adult, as …