Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term
LC Katzelnick, JV Zambrana, D Elizondo… - Science translational …, 2021 - science.org
Dengue virus serotypes 1 to 4 (DENV1–4) and Zika virus (ZIKV) are mosquito-borne
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …
flaviviruses that induce both virus-specific and broadly reactive antibodies. A first DENV …
Dengue virus envelope dimer epitope monoclonal antibodies isolated from dengue patients are protective against Zika virus
Zika virus (ZIKV) is a mosquito-borne flavivirus responsible for thousands of cases of severe
fetal malformations and neurological disease since its introduction to Brazil in 2013 …
fetal malformations and neurological disease since its introduction to Brazil in 2013 …
Longitudinal analysis of antibody cross-neutralization following Zika virus and dengue virus infection in Asia and the Americas
Background The 4 dengue virus serotypes (DENV1–4) and Zika virus (ZIKV) are related
mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies and …
mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies and …
Dengue virus antibodies enhance Zika virus infection
LM Paul, ER Carlin, MM Jenkins, AL Tan… - Clinical & …, 2016 - Wiley Online Library
For decades, human infections with Zika virus (ZIKV), a mosquito‐transmitted flavivirus, were
sporadic, associated with mild disease, and went underreported since symptoms were …
sporadic, associated with mild disease, and went underreported since symptoms were …
Maternally acquired Zika antibodies enhance dengue disease severity in mice
AM Fowler, WW Tang, MP Young, A Mamidi… - Cell host & …, 2018 - cell.com
Antibody (Ab)-dependent enhancement can exacerbate dengue virus (DENV) infection due
to cross-reactive Abs from an initial DENV infection, facilitating replication of a second …
to cross-reactive Abs from an initial DENV infection, facilitating replication of a second …
Zika virus infection enhances future risk of severe dengue disease
LC Katzelnick, C Narvaez, S Arguello… - Science, 2020 - science.org
The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …
Antigenic cross-reactivity between Zika and dengue viruses: is it time to develop a universal vaccine?
J Wen, S Shresta - Current opinion in immunology, 2019 - Elsevier
Zika and the four serotypes of dengue are closely related flaviviruses that share a high
degree of structural and sequence homology and co-circulate in many regions of the world …
degree of structural and sequence homology and co-circulate in many regions of the world …
[HTML][HTML] Primary exposure to Zika virus increases risk of symptomatic dengue virus infection with serotypes 2, 3, and 4 but not serotype 1
Infection with any of the four dengue virus serotypes (DENV1–4) can protect against or
enhance subsequent dengue depending on pre-existing antibodies and the subsequent …
enhance subsequent dengue depending on pre-existing antibodies and the subsequent …
Two is better than one: evidence for T-cell cross-protection between dengue and zika and implications on vaccine design
KS Subramaniam, S Lant, L Goodwin, A Grifoni… - Frontiers in …, 2020 - frontiersin.org
Dengue virus (DENV, family Flaviviridae, genus Flavivirus) exists as four distinct serotypes.
Generally, immunity after infection with one serotype is protective and lifelong, though …
Generally, immunity after infection with one serotype is protective and lifelong, though …
Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics
RA Aogo, JV Zambrana, N Sanchez, S Ojeda… - Science translational …, 2023 - science.org
Sequential infection with multiple dengue virus (DENV) serotypes is thought to induce
enduring protection against dengue disease. However, long-term antibody waning has been …
enduring protection against dengue disease. However, long-term antibody waning has been …