New techniques are on the horizon for the detection of small leukemic clones in both, acute
leukemias and myeloproliferative disorders. A promising approach is based on digital …

The digital polymerase chain reaction (dPCR) is considered to be the third-generation
polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of …

Abstract BACKGROUND Digital PCR (dPCR) is an increasingly popular manifestation of
PCR that offers a number of unique advantages when applied to preclinical research …

Digital PCR represents an example of the power of PCR and provides unprecedented
opportunities for molecular genetic analysis in cancer. The technique is to amplify a single …

Digital droplet PCR (ddPCR) is a recent version of quantitative PCR (QT-PCR), useful for
measuring gene expression, doing clonality assays and detecting hot spot mutations. In …

The latest incarnation of PCR, digital PCR (dPCR), 2 takes 2 decades of development in
enzyme chemistry and assay design and applies them with formidable precision and …

Digital polymerase chain reaction (dPCR) is an emerging technique for the absolute
quantification of target nucleic acids. dPCR got attention as a precise quantification tool in …

Real-time quantitative PCR (qPCR) has been widely implemented for molecular testing, but
there are still some inherent limitations that hamper its usefulness. Droplet digital PCR …

Abstract Summary Droplet Digital PCR (ddPCR) is a sensitive platform used to quantify
specific nucleic acid molecules amplified by polymerase chain reactions. Its sensitivity …

Detection of plasma circulating nucleic acids (CNAs) requires the use of extremely sensitive
and precise methods. The commonly used quantitative real-time polymerase chain reaction …