[HTML][HTML] Unveiling uterine aging: much more to learn

Y Wu, M Li, J Zhang, S Wang - Ageing Research Reviews, 2023 - Elsevier
Uterine aging is an important factor that impacts fertility, reproductive health, and uterus-
related diseases; however, it remains poorly explored. Functionally, these disturbances …

Ovarian aging: mechanisms and intervention strategies

Z Zhu, W Xu, L Liu - Medical Review, 2023 - degruyter.com
Ovarian reserve is essential for fertility and influences healthy aging in women. Advanced
maternal age correlates with the progressive loss of both the quantity and quality of oocytes …

Determinants of female reproductive senescence: differential roles for the ovary and the neuroendocrine axis

E Buyuk, E Nejat, G Neal-Perry - Seminars in reproductive …, 2010 - thieme-connect.com
Aging in women is a complex process that begins with the transition into reproductive
senescence and evolves to impact not just women's procreative potential but also multiple …

Female reproductive aging: from consequences to mechanisms, markers, and treatments

FE Duncan, R Confino, ME Pavone - Conn's handbook of models for human …, 2018 - Elsevier
Aging is universal and underlies chronic disease as well as tissue and cellular deterioration.
The female reproductive system is the first to age in humans, with functional decline …

The ageing ovary and uterus: new biological insights

SM Nelson, EE Telfer… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Advanced maternal age is associated with reduced fertility and adverse
pregnancy outcomes. This review details recent developments in our understanding of the …

Epigenetic clocks provide clues to the mystery of uterine ageing

PI Deryabin, AV Borodkina - Human Reproduction Update, 2023 - academic.oup.com
BACKGROUND Rising maternal ages and age-related fertility decline are a global
challenge for modern reproductive medicine. Clinicians and researchers pay specific …

Determinants of uterine aging: lessons from rodent models

SB Kong, S Zhang, YJ Chen, WX Wang… - Science China Life …, 2012 - Springer
The uterus is an indispensable organ for the development of a new life in eutherian
mammals. The female mammalian reproductive capacity diminishes with age. In this …

The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions

L Secomandi, M Borghesan, M Velarde… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Advanced maternal age is associated with decreased oocyte quantity and
quality as well as uterine and placental dysfunctions. These changes lead to infertility …

Longitudinal, epidemiologic studies of female reproductive aging

RJ Ferrell, MF Sowers - Annals of the New York Academy of …, 2010 - Wiley Online Library
Human female reproductive aging consists of multiple processes and interacts with other
physiological systems in unique ways. Here we discuss eight recent longitudinal …

Aging and reproductive senescence

LL Sievert - Reproductive ecology and human evolution, 2001 - books.google.com
Aging, as differentiated from disease, is progressive, irreversible, and universal (Kohn
1971). Senescence, a more restrictive term, refers to “a decrease in the efficient functioning …