Why and how physical activity promotes experience-induced brain plasticity

G Kempermann, K Fabel, D Ehninger, H Babu… - Frontiers in …, 2010 - frontiersin.org
Adult hippocampal neurogenesis is an unusual case of brain plasticity, since new neurons
(and not just neurites and synapses) are added to the network in an activity-dependent way …

Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis

A Garthe, I Roeder, G Kempermann - Hippocampus, 2016 - Wiley Online Library
We here show that living in a stimulus‐rich environment (ENR) improves water maze
learning with respect to specific key indicators that in previous loss‐of‐function experiments …

Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice

K Fabel, S Wolf, D Ehninger, H Babu… - Frontiers in …, 2009 - frontiersin.org
Voluntary physical exercise (wheel running, RUN) and environmental enrichment (ENR)
both stimulate adult hippocampal neurogenesis but do so by different mechanisms. RUN …

Intense exercise promotes adult hippocampal neurogenesis but not spatial discrimination

JH So, C Huang, M Ge, G Cai, L Zhang… - Frontiers in cellular …, 2017 - frontiersin.org
Hippocampal neurogenesis persists throughout adult life and plays an important role in
learning and memory. Although the influence of physical exercise on neurogenesis has …

Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function

AF Kramer, KI Erickson - Trends in cognitive sciences, 2007 - cell.com
Given the aging populations in many countries throughout the world, there is an increasing
interest in lifestyle factors and interventions that will enhance the cognitive vitality of older …

Physical activity and the regulation of neurogenesis in the adult and aging brain

K Fabel, G Kempermann - Neuromolecular medicine, 2008 - Springer
The discovery that exercise regulates adult hippocampal neurogenesis, that is, the
production of new neurons in the adult brain, was surprising news and changed quite …

Adaptive capacity: an evolutionary neuroscience model linking exercise, cognition, and brain health

DA Raichlen, GE Alexander - Trends in neurosciences, 2017 - cell.com
The field of cognitive neuroscience was transformed by the discovery that exercise induces
neurogenesis in the adult brain, with the potential to improve brain health and stave off the …

Hippocampal adult neurogenesis: Its regulation and potential role in spatial learning and memory

C Lieberwirth, Y Pan, Y Liu, Z Zhang, Z Wang - Brain research, 2016 - Elsevier
Adult neurogenesis, defined here as progenitor cell division generating functionally
integrated neurons in the adult brain, occurs within the hippocampus of numerous …

Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways

AK Olson, BD Eadie, C Ernst, BR Christie - Hippocampus, 2006 - Wiley Online Library
Environmental enrichment (EE) and voluntary exercise (VEx) have consistently been shown
to increase adult hippocampal neurogenesis and improve spatial learning ability. Although it …

Physical exercise induces hippocampal neurogenesis and prevents cognitive decline

CL Ma, XT Ma, JJ Wang, H Liu, YF Chen… - Behavioural brain …, 2017 - Elsevier
Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …