Altered levels of adipokines, derived as a result of distorted adipocytes, are the major factors
responsible for changing biochemical parameters in obesity that leads to the development of …

In the present study, we performed a differential proteomic analysis using 2‐DE combined
with MS to clarify the molecular mechanism for the suppressive effect of chitosan …

Objective Adipose tissue inflammation plays an important role in the pathogenesis of obesity-
associated complications, such as atherosclerosis. Adiponectin secreted from adipocytes …

Chitooligosaccharide (COS) is a natural product from the ocean, and while many studies
have reported its important role in metabolic diseases, no study has systematically …

Transcriptome analysis was performed to investigate the alterations in gene expression after
chitosan (CS) treatment on the liver of mice fed with high-fat diet (HFD). The results showed …

Obesity is a global disease that causes many metabolic disorders. However, effective agents
for the prevention or treatment of obesity remain limited. This study investigated the anti …

The 3T3-L1 cell line is a well-established and commonly used in vitro model to assess
adipocyte differentiation. Over the course of several days, confluent 3T3-L1 cells can be …

Excess body weight is a major risk factor for type 2 diabetes (T2D) and associated metabolic
complications, and weight loss has been shown to improve glycemic control and decrease …

Adiponectin, an abundant adipocyte-derived plasma protein that modulates vascular
function in type 2 diabetes, has been shown to provide cytoprotection to both pancreatic and …

The circulating concentrations of adiponectin, an antidiabetic adipokine, have been shown
to be reduced in obesity, in relation to an increase in inflammation. The aim of the present …