This review uses the National Cancer Institute (NCI) COMPARE program to establish an
extensive list of heterocyclic iminoquinones and quinones with similarities in differential …

A series of indolequinones bearing a range of substituents at the (indol-2-yl) methyl position
has been synthesized. The ability of these indolequinones to act as substrates for …

In the search for new potentially anticancer drugs, isoquinolinequinone-containing
polycyclic compounds have been designed and synthesized through highly regiocontrolled …

New 1H-pyrrolo [3, 2-c] quinoline-6, 9-diones, 11H-indolo [3, 2-c] quinoline-1, 4-diones and
7, 8, 9, 10-tetrahydro-11H-indolo [3, 2-c] quinoline-1, 4-diones, either unsubstituted or …

Our previous exploration of 2-phenylquinolin-4-ones (2-PQs) has led to an anticancer drug
candidate 2-(2-fluorophenyl)-6, 7-methylenedioxyquinolin-4-one monosodium phosphate …

A series of quinolinequinones bearing various substituents has been synthesized, and the
effects of substituents on the metabolism of the quinones by recombinant human NAD (P) H …

In the search of structure–activity relationship studies and to explore the antitumor effect
associated with the pyrimidoisoquinolinequinone scaffold, several diversily substituted 8 …

Presently cancer is a grave health issue with predominance beyond restrictions. It can affect
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …

Indole 12 was prepared in seven steps from para-anisidine. The key step was an
intramolecular nucleophilic aromatic substitution reaction. The group of natural products …

We herein describe the development and validation of an HPLC method for the quantitation
of 7‐(benzylamino)‐1, 3, 4, 8‐tetrahydropyrrolo [4, 3, 2‐de] quinolin‐8 (1H)‐one (BA‐TPQ) …