Radiotherapy is inevitably accompanied by some degree of radiation resistance, which
leads to local recurrence and even therapeutic failure. To overcome this limitation, herein …

Tumor hypoxia typically occurs inside a solid tumor with an inadequate oxygen supply,
sharply reducing the therapeutic efficiency of radiotherapy and significantly increasing the …

Chemodynamic therapy (CDT), which induces cell death by decomposing high levels of
H2O2 in tumor cells into highly toxic· OH, is recognized as a promising antineoplastic …

Full-process radiosensitization, that is, pre-increasing radiation sensitivity of cancer cells,
magnifying• OH formation during ionizing irradiation, and intervention on the resultant DNA …

The development of multifunctional nanoscale radiosensitizers has attracted a tremendous
amount of attention, which can enhance the radiosensitization of tumor tissues and reduce …

Superoxide dismutase (SOD) is one of the major antioxidants in vivo and is expected to play
critical roles on the defense against reactive oxygen species (ROS)-mediated damages …

Nanozyme‐based chemodynamic therapy (CDT) has emerged as an effective cancer
treatment because of its low side effects and without the requirement of exogenous energy …

Cancer deaths are mainly caused by tumor metastases. However, tumor ablation therapies
can only target the primary tumor but not inhibit tumor metastasis. Herein, a multifunctional …

The engineered nanoformulation that can be activated by intracellular tumor
microenvironment, including acidic pH, overexpressed H2O2, and high concentration of …

Radioresistance has always been a major factor for radiotherapy failure. Ferroptosis, as a
form of nonapoptotic programmed cell death, has been recently found being closely …