Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR

CL Holley, V Dhulipala, SA Maurakis, AN Greenawalt… - Mbio, 2023 - Am Soc Microbiol
Increasing antibiotic resistance of Neisseria gonorrhoeae, the causative agent of gonorrhea,
is a growing global concern that has renewed vaccine development efforts. The gonococcal …

[HTML][HTML] Transcriptional control of the gonococcal ompA gene by the MisR/MisS two-component regulatory system

CL Holley, JC Ayala, WM Shafer - Scientific reports, 2020 - nature.com
Neisseria gonorrhoeae, the causative agent of gonorrhea, is an exclusive human pathogen
whose growing antibiotic resistance is causing worldwide concern. The increasing rise of …

The ironclad truth: how in vivo transcriptomics and in vitro mechanistic studies shape our understanding of Neisseria gonorrhoeae gene regulation during mucosal …

MR Moreau, P Massari, CA Genco - Pathogens and disease, 2017 - academic.oup.com
Neisseria gonorrhoeae is one of the most prevalent sexually transmitted infections
worldwide. This obligate human pathogen has been extensively studied in vitro, where …

Characterization of the Neisseria gonorrhoeae iron and Fur regulatory network

C Yu, R McClure, K Nudel, N Daou… - Journal of …, 2016 - Am Soc Microbiol
The Neisseria gonorrhoeae f erric u ptake r egulator (Fur) protein controls expression of iron
homeostasis genes in response to intracellular iron levels. In this study, using transcriptome …

The Iron-Repressed, AraC-Like Regulator MpeR Activates Expression of fetA in Neisseria gonorrhoeae

A Hollander, AD Mercante, WM Shafer… - Infection and …, 2011 - Am Soc Microbiol
Neisseria gonorrhoeae is an obligate human pathogen that causes the common sexually
transmitted infection gonorrhea. Gonococcal infections cause significant morbidity …

Expression of the gonococcal global regulatory protein Fur and genes encompassing the Fur and iron regulon during in vitro and in vivo infection in women

S Agarwal, S Sebastian, B Szmigielski… - Journal of …, 2008 - Am Soc Microbiol
The ferric uptake regulatory protein, Fur, functions as a global regulatory protein of gene
transcription in the mucosal pathogen Neisseria gonorrhoeae. We have shown previously …

Both MisR (CpxR) and MisS (CpxA) are required for Neisseria gonorrhoeae infection in a murine model of lower genital tract infection

D Gangaiah, EL Raterman, H Wu… - Infection and …, 2017 - Am Soc Microbiol
During infection, Neisseria gonorrhoeae senses and responds to stress; such responses
may be modulated by MisRS (NGO0177 and NGO0176), a two-component system that is a …

Neisseria prophage repressor implicated in gonococcal pathogenesis

N Daou, C Yu, R Mcclure, C Gudino… - Infection and …, 2013 - Am Soc Microbiol
Neisseria gonorrhoeae, the causative agent of the sexually transmitted disease gonorrhea,
can infect and colonize multiple mucosal sites in both men and women. The ability to cope …

Transcript analysis of nrrF, a Fur repressed sRNA of Neisseria gonorrhoeae

TF Ducey, L Jackson, J Orvis, DW Dyer - Microbial pathogenesis, 2009 - Elsevier
Like most microorganisms, Neisseria gonorrhoeae alters gene expression in response to
iron availability. The ferric uptake regulator Fur has been shown to be involved in controlling …

Characterization of the OxyR regulon of Neisseria gonorrhoeae

KL Seib, HJ Wu, YN Srikhanta, JL Edwards… - Molecular …, 2007 - Wiley Online Library
OxyR regulates the expression of the majority of H2O2 responses in Gram‐negative
organisms. In a previous study we reported the OxyR‐dependent derepression of catalase …